Rabbit Polyclonal antibody to IKBKEIKBKE is a noncanonical I-kappa-B (see MIM 164008) kinase (IKK) that is essential for regulating antiviral signaling pathways. IKBKE has also been identified as a breast cancer (MIM 114480) oncogene and is amplified and overexpressed in over 30% of breast carcinomas and breast cancer cell lines (Hutti et al., 2009 [PubMed 19481526]).[supplied by OMIM, Oct 2009]
Immunogen
Recombinant protein of human IKBKE
Key Feature
Clonality
Polyclonal
Isotype
IgG
Host Species
Rabbit
Tested Applications
IHC-PWB
WB: 1:500 - 1:2000, IHC: 1:50 - 1:200
Species Reactivity
HumanMouseRat
Concentration
1mg/ml
Purification
Affinity purified
Target Information
Gene Synonyms
IKKE , IKK E , IKKI , IKK i , inhibitor of kappa light polypeptide gene enhancer in B-cells, kinase epsilon
Target
IKBKE
Application
Application
Western blot analysis of extracts of various cell lines, using IKBKE antibody.