| Product Name | IKBKE antibody |
|---|---|
| Antibody Type | Primary Antibodies |
| Product description | Rabbit polyclonal to IKBKENuclear factor kappa B (NF-kB) is a ubiquitous transcription factor and an essential mediator of gene expression during activation of immune and inflammatory responses. NF-kB mediates the expression of a great variety of genes in response to extracellular stimuli. NF-kB is associated with IkB proteins in the cell cytoplasm, which inhibit NF-kB activity. IkB is phosphorylated by IkB kinase(IKK) complex that contains IKKa, IKKb, and IKKg. A novel molecule in the IKK complex was recently identified and designated IKKe/IKK-i (1,2). IKKe is required for the activation of NF-kB by PMA and T cell receptors but not by TNFa and IL-1 (1). IKKe/IKK-i message is expressed in a variety of tissues and is inducible by TNFa, IL-1, and LPS (2). |
| Immunogen | Peptide: amino acids 705-716 of human IKK epsilon |
| Clonality | Polyclonal |
|---|---|
| Isotype | IgG |
| Host Species | Rabbit |
| Tested Applications | WB |
| For WB: Use at a dilution of 1:500-1:1,000. Optimal dilutions/concentrations should be determined by the researcher. | |
| Species Reactivity | Human |
| Concentration | 0.5mg/ml |
| Purification | Affinity purified |
| Gene Synonyms | IKK-E, IKK-i, IKKE, IKKI, KIAA0151, MGC125294, MGC125295, MGC125297, IKK E, IKK i |
|---|---|
| Target | IKK epsilon |
| Tissue Specificity | IKK epsilon - Does not cross react with IKK alpha, beta or gamma |
| Application Notes | For WB: Use at a dilution of 1:500-1:1,000. Optimal dilutions/concentrations should be determined by the researcher. |
|---|
| Form | Liquid |
|---|---|
| Storage Instructions | Keep as concentrated solution. Aliquot and store at -20ºC or below. Avoid freeze-thaw cycles. |
| Storage Buffer | Phosphate-buffered saline, pH 7.4, containing 0.02% sodium azide |
