Rabbit polyclonal to IKBKEThis member of the Ser/Thr protein kinase family (IkappaB kinase subfamily) phosphorylates inhibitors of NF-kappa-B thus leading to the dissociation of the inhibitor/NF-kappa-B complex and ultimately the degradation of the inhibitor. It is highly expressed in spleen followed by thymus, peripheral blood leukocytes, pancreas, placenta, and may play a special role in the immune response; it is weakly expressed in lung, kidney, prostate, ovary and colon.
Immunogen
This antibody was raised against a synthetic peptide corresponding to amino acid residue(s) 175-188, 525-540, and 567-580 of human IKKe/IKKi.
Key Feature
Clonality
Polyclonal
Isotype
IgG
Host Species
Rabbit
Tested Applications
WB
Based on the sequence similarity, it may cross react with TBK1. :
Species Reactivity
Human
Concentration
0.5mg/ml
Purification
Affinity purified
Target Information
Gene Synonyms
IKK-E IKK-i IKKE IKKI KIAA0151 MGC125294 MGC125295 MGC125297 IKK E IKK i
Target
IKKe/IKKi
Cellular Localization
Cytoplasmic
Application
Application
Western blot analysis of IKKe in Daudi lysate using IKKe antibody at 2 ug/ml.
Application Notes
Based on the sequence similarity, it may cross react with TBK1. :
Additional Information
Form
Liquid
Storage Instructions
Keep as concentrated solution. Store at 4ºC short term. For extended storage aliquot and store at -20ºC or below. Avoid freeze-thaw cycles.