Application
Figure 1: Western blot analysis using IKBKE monoclonal antiobdy against truncated IKBKE recombinant protein(1) and full-length IKBKE(aa1-716)-hIgGFc transfected COS7 cell lysate(2).| Product Name | IKBKE Antibody |
|---|---|
| Antibody Type | Primary Antibodies |
| Antigen Alias | IKBKE |
| Clonality | Monoclonal |
|---|---|
| Isotype | IgG1 |
| Clone Number | 6B4B5 |
| Host Species | Mouse |
| Tested Applications | WB |
| WB:1:500 - 2000. |
|
| Species Reactivity | Human |
| Concentration | 1mg/ml |
| Gene Synonyms | IKKE IKKI KIAA0151 |
|---|---|
| Alternative Names | IKBKE |
| Molecular Weight(MW) | 80462 Da |
| Function | Phosphorylates inhibitors of NF-kappa-B thus leading to the dissociation of the inhibitor/NF-kappa-B complex and ultimately the degradation of the inhibitor. May play a special role in the immune response. Protects cells against DNA damage- induced cell death |
| Tissue Specificity | Highly expressed in spleen followed by thymus, peripheral blood leukocytes, pancreas, placenta. Weakly expressed in lung, kidney, prostate, ovary and colon |
| Cellular Localization | Cytoplasm. Nucleus. Nucleus, PML body. Note=Targeting to PML nuclear bodies upon DNA damage is TOPORS- dependent |
| Entrez Gene | 9641 |
|---|---|
| Nucleotide Accession | NP_054721.1 |
Application
Figure 1: Western blot analysis using IKBKE monoclonal antiobdy against truncated IKBKE recombinant protein(1) and full-length IKBKE(aa1-716)-hIgGFc transfected COS7 cell lysate(2).| Application Notes | WB:1:500 - 2000. |
|---|
| Form | Liquid |
|---|---|
| Storage Instructions | For short-term storage, store at 4° C. For long-term storage, aliquot and store at -20ºC or below. Avoid multiple freeze-thaw cycles. |
| Storage Buffer | Purified recombinant fragment of IKBKE(aa1-257) expressed in E. Coli. |
