Application
Western blot analysis of IKK- alpha /IKK- beta phosphorylation expression in TNF treated NIH-3T3 whole cell lysates,The lane on the left is treated with the antigen-specific peptide.| Product Name | IKK alpha (phospho Ser176) /IKK- beta (phospho Ser177) antibody |
|---|---|
| Antibody Type | Primary Antibodies |
| Product description | Rabbit Polyclonal antibody to IKK- beta (phospho Ser177)This gene encodes a member of the serine/threonine protein kinase family. The encoded protein, a component of a cytokine-activated protein complex that is an inhibitor of the essential transcription factor NF-kappa-B complex, phosphorylates sites that trigger the degradation of the inhibitor via the ubiquination pathway, thereby activating the transcription factor. [provided by RefSeq, Jul 2008] |
| Immunogen | A synthesized peptide derived from human IKK- beta around the phosphorylation site of Ser177 |
| Modification | p-Ser177 |
| Clonality | Polyclonal |
|---|---|
| Isotype | IgG |
| Host Species | Rabbit |
| Tested Applications | IHCWB |
| WB 1:500-1:2000, IHC 1:50-1:200: |
|
| Species Reactivity | HumanMouseRat |
| Concentration | 1mg/ml (Please refer to the vial label for the specific concentration) |
| Purification | Affinity purified |
| Gene Synonyms | IKK alpha (phospho Ser176) /IKK- beta (phospho Ser177) (phospho S177) Phospho Ser177 IKK alpha (phospho Ser176) /IKK- beta (phospho Ser177) NFKBIKA IKK alpha (phospho Ser176) /IKK- beta (phospho Ser177) S177 Phospho |
|---|---|
| Target | IKK alpha (phospho Ser176) /IKK- beta (phospho Ser177) |
| Tissue Specificity | CHUK |
Application
Western blot analysis of IKK- alpha /IKK- beta phosphorylation expression in TNF treated NIH-3T3 whole cell lysates,The lane on the left is treated with the antigen-specific peptide.| Application Notes | WB 1:500-1:2000, IHC 1:50-1:200: |
|---|
| Form | Liquid |
|---|---|
| Storage Instructions | Keep as concentrated solution. Aliquot and store at -20ºC or below. Avoid multiple freeze-thaw cycles. |
| Storage Buffer | phosphate buffered saline , pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol. |
