Application
Immunohistochemical analysis of paraffin-embedded human colon carcinoma, using IL10 Receptor alpha antibody at 1:250 dilution.Application
Sample (30 ug of whole cell lysate) A: Hep G2 7.5% SDS PAGE IL-10R alpha antibody diluted at 1:1000| Product Name | IL10 Receptor alpha antibody |
|---|---|
| Antibody Type | Primary Antibodies |
| Product description | Rabbit Polyclonal antibody to IL10 Receptor alpha (interleukin 10 receptor, alpha)The protein encoded by this gene is a receptor for interleukin 10. This protein is structurally related to interferon receptors. It has been shown to mediate the immunosuppressive signal of interleukin 10, and thus inhibits the synthesis of proinflammatory cytokines. This receptor is reported to promote survival of progenitor myeloid cells through the insulin receptor substrate-2/PI 3-kinase/AKT pathway. Activation of this receptor leads to tyrosine phosphorylation of JAK1 and TYK2 kinases. Two transcript variants, one protein-coding and the other not protein-coding, have been found for this gene. [provided by RefSeq] |
| Immunogen | Recombinant protein encompassing a sequence within the center region of human IL10 Receptor alpha. The exact sequence is proprietary. |
| Clonality | Polyclonal |
|---|---|
| Isotype | IgG |
| Host Species | Rabbit |
| Tested Applications | IHC-PWB |
| *Optimal dilutions/concentrations should be determined by the researcher.
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| Species Reactivity | Human |
| Concentration | 1mg/ml (Please refer to the vial label for the specific concentration) |
| Purification | Affinity purified |
| Gene Synonyms | CDW210A antibody HIL-10R antibody IL-10R1 antibody IL10R antibody IL10RA antibody IL-10RA antibody interleukin-10 receptor subunit 1 antibody interleukin-10 receptor alpha chain antibody IL-10 receptor subunit alpha antibody IL-10R subunit alpha a |
|---|---|
| Molecular Weight(MW) | 63 kDa (note) |
| Cellular Localization | Membrane; Single-pass type I membrane protein |
Application
Immunohistochemical analysis of paraffin-embedded human colon carcinoma, using IL10 Receptor alpha antibody at 1:250 dilution.
Application
Sample (30 ug of whole cell lysate) A: Hep G2 7.5% SDS PAGE IL-10R alpha antibody diluted at 1:1000| Positive Control | HepG2 , HCT116 |
|---|---|
| Application Notes | *Optimal dilutions/concentrations should be determined by the researcher.
: |
| Form | Liquid |
|---|---|
| Storage Instructions | Keep as concentrated solution. Aliquot and store at -20ºC or below. Avoid multiple freeze-thaw cycles. |
| Storage Buffer | 0.1M Tris, 0.1M Glycine, 10% Glycerol (pH7). 0.01% Thimerosal was added as a preservative. |
