Application
Western blot analysis of extracts of various cell lines, using IL12RB1 antibody.Application
Immunohistochemistry of paraffin-embedded rat kidney using IL12RB1 antibody at dilution of 1:200 (400x lens).Application
Immunofluorescence analysis of A549 cell using IL12RB1 antibody. Blue: DAPI for nuclear staining.| Product Name | IL12 Receptor beta1 antibody |
|---|---|
| Antibody Type | Primary Antibodies |
| Product description | Rabbit Polyclonal antibody to IL12 Receptor beta1The protein encoded by this gene is a type I transmembrane protein that belongs to the hemopoietin receptor superfamily. This protein binds to interleukine 12 (IL12) with a low affinity, and is thought to be a part of IL12 receptor complex. This protein forms a disulfide-linked oligomer, which is required for its IL12 binding activity. The coexpression of this and IL12RB2 proteins was shown to lead to the formation of high-affinity IL12 binding sites and reconstitution of IL12 dependent signaling. Mutations in this gene impair the development of interleukin-17-producing T lymphocytes and result in increased susceptibility to mycobacterial and Salmonella infections. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Feb 2014] |
| Immunogen | Recombinant protein of human IL12RB1 |
| Clonality | Polyclonal |
|---|---|
| Isotype | IgG |
| Host Species | Rabbit |
| Tested Applications | ICC/IFIHCIHC-PWB |
| WB: 1:500 - 1:2000, IHC: 1:50 - 1:200, IF: 1:10 - 1:100: |
|
| Species Reactivity | HumanMouseRat |
| Concentration | 1mg/ml |
| Purification | Affinity purified |
| Gene Synonyms | IL12RB IL12R BETA1 interleukin 12 receptor subunit beta 1 CD212 IL12RB1 |
|---|---|
| Target | IL12 Receptor beta1 |
Application
Western blot analysis of extracts of various cell lines, using IL12RB1 antibody.
Application
Immunohistochemistry of paraffin-embedded rat kidney using IL12RB1 antibody at dilution of 1:200 (400x lens).
Application
Immunofluorescence analysis of A549 cell using IL12RB1 antibody. Blue: DAPI for nuclear staining.| Application Notes | WB: 1:500 - 1:2000, IHC: 1:50 - 1:200, IF: 1:10 - 1:100: |
|---|
| Form | Liquid |
|---|---|
| Storage Instructions | Store at -20℃. Avoid freeze / thaw cycles. |
| Storage Buffer | PBS with 0.02% sodium azide, 50% glycerol, pH7.3. |
