Application
Western blot analysis of IL17RA in A20 cell lysate with IL17RA antibody at 1 μg/mL.Application
Immunofluorescence of IL-17RA in human spleen tissue with IL-17RA antibody at 20 μg/ml.Application
Immunohistochemistry of IL-17RA in human spleen tissue with IL-17RA antibody at 2.5 μg/ml.| Product Name | IL17 Receptor alpha antibody |
|---|---|
| Antibody Type | Primary Antibodies |
| Product description | Rabbit Polyclonal antibody to IL-17RAInterleukin 17A (IL17A)is a proinflammatory cytokine secreted by activated T-lymphocytes. It is a potent inducer of the maturation of CD34-positive hematopoietic precursors into neutrophils. The protein encoded by this gene (interleukin 17A receptor; IL17RA) is a ubiquitous type I membrane glycoprotein that binds with low affinity to interleukin 17A. Interleukin 17A and its receptor play a pathogenic role in many inflammatory and autoimmune diseases such as rheumatoid arthritis. Like other cytokine receptors, this receptor likely has a multimeric structure. [provided by RefSeq, Jul 2008] |
| Immunogen | IL-17RA antibody was raised against an 18 amino acid peptide near the amino terminus of human IL-17RA. |
| Clonality | Polyclonal |
|---|---|
| Isotype | IgG |
| Host Species | Rabbit |
| Tested Applications | ICC/IFIHC-PWB |
| We recommend the following starting dilutions: For WB: Use at a concentration of 1 - 2 ug/mL. For IHC-P: Use at a concentration of 2.5µg/mL. For ICC/IF: Use at a concentration of 20µg/mL. Optimal dilutions should be determined experimentally by the end user.: |
|
| Species Reactivity | HumanMouseRat |
| Concentration | 1mg/ml |
| Gene Synonyms | CDw217 IL17R CD217 CANDF5 hIL-17R interleukin 17 receptor A IL17RA |
|---|---|
| Target | IL-17RA |
| Tissue Specificity | IL-17RA antibody is human, mouse and rat reactive. Multiple isoforms of IL-17RA are known to exist. This antibody is predicted to not cross-react with other IL-17 receptor subunits. |
Application
Western blot analysis of IL17RA in A20 cell lysate with IL17RA antibody at 1 μg/mL.
Application
Immunofluorescence of IL-17RA in human spleen tissue with IL-17RA antibody at 20 μg/ml.
Application
Immunohistochemistry of IL-17RA in human spleen tissue with IL-17RA antibody at 2.5 μg/ml.| Application Notes | We recommend the following starting dilutions: For WB: Use at a concentration of 1 - 2 ug/mL. For IHC-P: Use at a concentration of 2.5µg/mL. For ICC/IF: Use at a concentration of 20µg/mL. Optimal dilutions should be determined experimentally by the end user.: |
|---|
| Form | Liquid |
|---|---|
| Storage Instructions | IL-17RA antibody can be stored at 4˚C for three months and -20˚C, stable for up to one year. |
| Storage Buffer | PBS containing 0.02% sodium azide. |
