| Product Name | IL18 Receptor 1 antibody |
|---|---|
| Antibody Type | Primary Antibodies |
| Product description | Mouse monoclonal antibody [8H22] to IL-18R alphaThe protein encoded by this gene is a cytokine receptor that belongs to the interleukin 1 receptor family. This receptor specifically binds interleukin 18 (IL18), and is essential for IL18 mediated signal transduction. IFN-alpha and IL12 are reported to induce the expression of this receptor in NK and T cells. This gene along with four other members of the interleukin 1 receptor family, including IL1R2, IL1R1, ILRL2 (IL-1Rrp2), and IL1RL1 (T1/ST2), form a gene cluster on chromosome 2q. [provided by RefSeq, Jul 2008] |
| Immunogen | Human recombinant IL-18R alpha EC domain |
| Clonality | Monoclonal |
|---|---|
| Isotype | IgG1 |
| Clone Number | 8H22 |
| Host Species | Mouse |
| Tested Applications | IHCNeutWB |
| WB(1:500-2000)|IHC (paraffin)(1:20-100)|Neutralization of IL-18R alpha signaling: |
|
| Species Reactivity | Human |
| Concentration | 1mg/ml |
| Purification | Affinity purified |
| Gene Synonyms | CD218a interleukin 18 receptor 1 IL18R1 IL-1Rrp IL1RRP CDw218a IL18RA |
|---|---|
| Target | IL-18R alpha |
| Tissue Specificity | This antibody was selected for its ability to detect human IL-18 R alpha. |
| Application Notes | WB(1:500-2000)|IHC (paraffin)(1:20-100)|Neutralization of IL-18R alpha signaling: |
|---|
| Form | Liquid |
|---|---|
| Storage Instructions | Keep as concentrated solution. Aliquot and store at -20ºC or below. Avoid multiple freeze-thaw cycles. |
| Storage Buffer | PBS |
