| Product Name | IL21 antibody |
|---|---|
| Antibody Type | Primary Antibodies |
| Product description | Rabbit polyclonal to IL21A novel cytokine related to IL2 and IL15 was recently identified and designated IL21. The receptor for IL21 (IL21R, also termed NILR for novel Interleukin receptor) is a new member of the class I cytokine receptor family. IL21R forms a complex with the common cytokine receptor g chain, gc, and mediates IL21 signaling. Both IL21R and the gc are necessary for the IL21 function. IL21 and its receptor activate JAKSTAT signaling pathway. IL21R is expressed in spleen, thymus, natural killer (NK), T and B cell lines. IL21 plays a role in the proliferation and maturation of NK, B and T cell populations. |
| Immunogen | Synthetic peptide: CDSYEKKPPKEFLERFKSLLQKMIHQHLS, corresponding to C terminal amino acids 118-146 of Human IL21. |
| Clonality | Polyclonal |
|---|---|
| Isotype | IgG |
| Host Species | Rabbit |
| Tested Applications | ELISAICC/IF |
| For ELISA (peptide): Use at a dilution of 1:100,000. This product can also be used for native human IL-21 in combination with product GTX82914. For ICC: Use at a dilution of 1:500. Optimal dilutions/concentrations should be determined by the researcher.: |
|
| Species Reactivity | Human |
| Concentration | 1mg/ml (Please refer to the vial label for the specific concentration) |
| Purification | Affinity purified |
| Target | IL21 |
|---|---|
| Tissue Specificity | Peptide sequence is |
| Positive Control | Human spleen cells |
|---|---|
| Application Notes | For ELISA (peptide): Use at a dilution of 1:100,000. This product can also be used for native human IL-21 in combination with product GTX82914. For ICC: Use at a dilution of 1:500. Optimal dilutions/concentrations should be determined by the researcher.: |
| Form | Liquid |
|---|---|
| Storage Instructions | Aliquot and store at 4°C or freeze at -20° C. For long term storage freeze at -70° C. Avoid freeze-thaw cycles. and store at -20°C long-term. |
| Storage Buffer | 10 mM KHPO4 and 140 mM NaCl containing 0.1% sodium azide |
