Application
Sample (30 ug of whole cell lysate) A: A431 12% SDS PAGE diluted at 1:1000Application
Interleukin-24 antibody [C2C3], C-term detects Interleukin-24 protein at cytoplasm in human cervical carcinoma by immunohistochemical analysis. Sample: Paraffin-embedded human cervical carcinoma. Interleukin-24 antibody [C2C3], C-term diluted at 1:500.Application
Interleukin-24 antibody [C2C3], C-term detects Interleukin-24 protein at cytoplasm in human esophageal cancer by immunohistochemical analysis. Sample: Paraffin-embedded human esophageal cancer. Interleukin-24 antibody [C2C3], C-term diluted at 1:400.| Product Name | IL24 antibody [C2C3], C-term |
|---|---|
| Antibody Type | Primary Antibodies |
| Product description | Rabbit polyclonal antibody to Interleukin-24 (interleukin 24)This gene encodes a member of the IL10 family of cytokines. It was identified as a gene induced during terminal differentiation in melanoma cells. The protein encoded by this gene can induce apoptosis selectively in various cancer cells. Overexpression of this gene leads to elevated expression of several GADD family genes, which correlates with the induction of apoptosis. The phosphorylation of mitogen-activated protein kinase 14 (MAPK7/P38), and heat shock 27kDa protein 1 (HSPB2/HSP27) are found to be induced by this gene in melanoma cells, but not in normal immortal melanocytes. Alternatively spliced transcript variants encoding distinct isoforms have been reported. [provided by RefSeq] |
| Immunogen | Carrier-protein conjugated synthetic peptide encompassing a sequence within the C-terminus region of human Interleukin-24. The exact sequence is proprietary. |
| Clonality | Polyclonal |
|---|---|
| Isotype | IgG |
| Host Species | Rabbit |
| Tested Applications | IHC-PWB |
| *Optimal dilutions/concentrations should be determined by the researcher. | |
| Species Reactivity | Human |
| Predicted Reactivity | Mouse, RatMouse (93%), Rat (80%) |
| Concentration | 1mg/ml |
| Purification | Affinity purified |
| Gene Synonyms | C49A antibody, FISP antibody, IL10B antibody, MDA7 antibody, MOB5 antibody, ST16 antibody, IL24 antibody, melanocyte-associated Mda-7 antibody, suppression of tumorigenicity 16 (melanoma differentiation) antibody, interleukin-24 antibody, melanoma differen |
|---|---|
| Target | Interleukin-24 |
| Molecular Weight(MW) | 24 kDa (note) (3) |
| Cellular Localization | Secreted |
Application
Sample (30 ug of whole cell lysate) A: A431 12% SDS PAGE diluted at 1:1000
Application
Interleukin-24 antibody [C2C3], C-term detects Interleukin-24 protein at cytoplasm in human cervical carcinoma by immunohistochemical analysis. Sample: Paraffin-embedded human cervical carcinoma. Interleukin-24 antibody [C2C3], C-term diluted at 1:500.
Application
Interleukin-24 antibody [C2C3], C-term detects Interleukin-24 protein at cytoplasm in human esophageal cancer by immunohistochemical analysis. Sample: Paraffin-embedded human esophageal cancer. Interleukin-24 antibody [C2C3], C-term diluted at 1:400.| Positive Control | A431 |
|---|---|
| Application Notes | *Optimal dilutions/concentrations should be determined by the researcher. |
| Form | Liquid |
|---|---|
| Storage Instructions | Keep as concentrated solution. Aliquot and store at -20oC or below. Avoid multiple freeze-thaw cycles. |
| Storage Buffer | 0.1M Tris, 0.1M Glycine, 10% Glycerol (pH7). 0.01% Thimerosal was added as a preservative. |
