| Product Name | IL5 Receptor alpha antibody |
|---|---|
| Antibody Type | Primary Antibodies |
| Product description | Mouse monoclonal antibody [6J30] to IL-5R alphaThe protein encoded by this gene is an interleukin 5 specific subunit of a heterodimeric cytokine receptor. The receptor is comprised of a ligand specific alpha subunit and a signal transducing beta subunit shared by the receptors for interleukin 3 (IL3), colony stimulating factor 2 (CSF2/GM-CSF), and interleukin 5 (IL5). The binding of this protein to IL5 depends on the beta subunit. The beta subunit is activated by the ligand binding, and is required for the biological activities of IL5. This protein has been found to interact with syndecan binding protein (syntenin), which is required for IL5 mediated activation of the transcription factor SOX4. Several alternatively spliced transcript variants encoding four distinct isoforms have been reported. [provided by RefSeq, Jul 2011] |
| Immunogen | Human recombinant IL-5R alpha EC domain |
| Clonality | Monoclonal |
|---|---|
| Isotype | IgG1 |
| Clone Number | 6J30 |
| Host Species | Mouse |
| Tested Applications | WB |
| WB(1:500-1000): |
|
| Species Reactivity | Human |
| Concentration | 1mg/ml |
| Purification | Affinity purified |
| Gene Synonyms | interleukin 5 receptor alpha HSIL5R3 CDw125 IL5RA CD125 IL5R |
|---|---|
| Target | IL-5R alpha |
| Tissue Specificity | This antibody was selected for its ability to detect human IL-5R alpha. |
| Application Notes | WB(1:500-1000): |
|---|
| Form | Liquid |
|---|---|
| Storage Instructions | Keep as concentrated solution. Aliquot and store at -20ºC or below. Avoid multiple freeze-thaw cycles. |
| Storage Buffer | PBS |
