Application
WB analysis of extracts from various cells using ING3 antibody.Application
ICC/IF analysis of A549 cells using ING3 antibody (green) and DAPI (blue).| Product Name | ING3 antibody |
|---|---|
| Antibody Type | Primary Antibodies |
| Product description | Rabbit Polyclonal antibody to ING3The protein encoded by this gene is similar to ING1, a tumor suppressor protein that can interact with TP53, inhibit cell growth, and induce apoptosis. This protein contains a PHD-finger, which is a common motif in proteins involved in chromatin remodeling. This gene can activate p53 trans-activated promoters, including promoters of p21/waf1 and bax. Overexpression of this gene has been shown to inhibit cell growth and induce apoptosis. Allelic loss and reduced expression of this gene were detected in head and neck cancers. Two alternatively spliced transcript variants encoding different isoforms have been observed. [provided by RefSeq, Jul 2008] |
| Immunogen | Recombinant protein of human ING3 |
| Clonality | Polyclonal |
|---|---|
| Isotype | IgG |
| Host Species | Rabbit |
| Tested Applications | ICC/IFIHC-PIPWB |
| WB: 1:500 - 1:2000. IHC: 1:50 - 1:200. IP: 1:50 - 1:100. IF: 1:50 - 1:200: |
|
| Species Reactivity | HumanMouseRat |
| Concentration | 1mg/ml |
| Purification | Affinity purified |
| Gene Synonyms | Eaf4 ING2 MEAF4 p47ING3 inhibitor of growth family member 3 |
|---|---|
| Target | ING3 |
| Molecular Weight(MW) | 46 kDa (note) |
Application
WB analysis of extracts from various cells using ING3 antibody.
Application
ICC/IF analysis of A549 cells using ING3 antibody (green) and DAPI (blue).| Application Notes | WB: 1:500 - 1:2000. IHC: 1:50 - 1:200. IP: 1:50 - 1:100. IF: 1:50 - 1:200: |
|---|
| Form | Liquid |
|---|---|
| Storage Instructions | Store at -20°C (regular) or -80°C (long term). Avoid freeze / thaw cycles. |
| Storage Buffer | PBS with 0.02% sodium azide, 50% glycerol, pH7.3. |
