Application
Western blot analysis of extracts from 293 cells treated with Heatstock using IR (Phospho-Tyr1361) Antibody. The lane on the right is treated with the antigen-specific peptide.| Product Name | Insulin Receptor (phospho Tyr1361) antibody |
|---|---|
| Antibody Type | Primary Antibodies |
| Product description | Rabbit Polyclonal antibody to Insulin Receptor (phospho Tyr1361)After removal of the precursor signal peptide, the insulin receptor precursor is post-translationally cleaved into two chains (alpha and beta) that are covalently linked. Binding of insulin to the insulin receptor (INSR) stimulates glucose uptake. Two transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Jul 2008] |
| Immunogen | Peptide sequence around phosphorylation site of Tyrosine 1361 (I-P-Y(p)-T-H) derived from Human IR. |
| Modification | p-Tyr1361 |
| Clonality | Polyclonal |
|---|---|
| Isotype | IgG |
| Host Species | Rabbit |
| Tested Applications | WB |
| WB: 1:500 - 1:1000: |
|
| Species Reactivity | HumanMouseRat |
| Concentration | 1mg/ml (Please refer to the vial label for the specific concentration) |
| Purification | Affinity purified |
| Gene Synonyms | HHF5 INSR insulin receptor CD220 |
|---|---|
| Target | Insulin Receptor (phospho Tyr1361) |
| Tissue Specificity | The antibody detects endogenous level of IR only when phosphorylated at Tyrosine 1361. |
Application
Western blot analysis of extracts from 293 cells treated with Heatstock using IR (Phospho-Tyr1361) Antibody. The lane on the right is treated with the antigen-specific peptide.| Application Notes | WB: 1:500 - 1:1000: |
|---|
| Form | Liquid |
|---|---|
| Storage Instructions | Store at -20˚C/1 year |
| Storage Buffer | Supplied at 1.0mg/mL in phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol. |
