Mouse monoclonal antibody [16B4] to Integrin alpha 2This gene encodes the alpha subunit of a transmembrane receptor for collagens and related proteins. The encoded protein forms a heterodimer with a beta subunit and mediates the adhesion of platelets and other cell types to the extracellular matrix. Loss of the encoded protein is associated with bleeding disorder platelet-type 9. Antibodies against this protein are found in several immune disorders, including neonatal alloimmune thrombocytopenia. This gene is located adjacent to a related alpha subunit gene. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Aug 2012]
Key Feature
Clonality
Monoclonal
Isotype
IgG1
Clone Number
16B4
Host Species
Mouse
Tested Applications
ELISAFACSICC/IFIHC-FIHC-PIPWBFunctional Assay
ELISA: Max Dilution 10 ug/ml:
Species Reactivity
Human
Concentration
1mg/ml
Purification
Affinity purified
Target Information
Gene Synonyms
HPA-5 CD49B VLAA2 VLA-2 GPIA ITGA2 BR
Target
CD49b
Tissue Specificity
This antibody recognizes human Integrin alpha 2.
Application
Application
FACS analysis of human peripheral blood platelets using Integrin alpha 2 antibody [16B4].
Application Notes
ELISA: Max Dilution 10 ug/ml:
Additional Information
Form
Liquid
Storage Instructions
Store at +4°C or at -20°C if preferred. This product should be stored undiluted. Storage in frost-free freezers is not recommended. Avoid repeated freezing and thawing as this may denature the antibody. Should this product contain a precipitate we recommend microcentrifugation before use.