Mouse monoclonal antibody [AK7] to Integrin alpha 2This gene encodes the alpha subunit of a transmembrane receptor for collagens and related proteins. The encoded protein forms a heterodimer with a beta subunit and mediates the adhesion of platelets and other cell types to the extracellular matrix. Loss of the encoded protein is associated with bleeding disorder platelet-type 9. Antibodies against this protein are found in several immune disorders, including neonatal alloimmune thrombocytopenia. This gene is located adjacent to a related alpha subunit gene. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Aug 2012]
Key Feature
Clonality
Monoclonal
Isotype
IgG1
Clone Number
AK7
Host Species
Mouse
Tested Applications
FACSIHC-FFunctional Assay
Flow Cytometry: 1/50 - 1/100:
Species Reactivity
HumanBaboonRhesus MonkeyCynomolgus Monkey
Concentration
1mg/ml
Purification
Affinity purified
Target Information
Gene Synonyms
HPA-5 CD49B VLAA2 VLA-2 GPIA BR ITGA2
Target
CD49b
Tissue Specificity
This antibody recognizes the integrin alpha 2 subunit.
Application Notes
Flow Cytometry: 1/50 - 1/100:
Additional Information
Form
Liquid
Storage Instructions
Store at +4°C or at -20°C if preferred. This product should be stored undiluted. Storage in frost-free freezers is not recommended. Avoid repeated freezing and thawing as this may denature the antibody. Should this product contain a precipitate we recommend microcentrifugation before use.