| Product Name | Integrin alpha E antibody |
|---|---|
| Antibody Type | Primary Antibodies |
| Product description | Mouse monoclonal antibody [2G5.1] to Integrin alpha EIntegrins are heterodimeric integral membrane proteins composed of an alpha chain and a beta chain. This gene encodes an I-domain-containing alpha integrin that undergoes post-translational cleavage in the extracellular domain, yielding disulfide-linked heavy and light chains. In combination with the beta 7 integrin, this protein forms the E-cadherin binding integrin known as the human mucosal lymphocyte-1 antigen. This protein is preferentially expressed in human intestinal intraepithelial lymphocytes (IEL), and in addition to a role in adhesion, it may serve as an accessory molecule for IEL activation. [provided by RefSeq, Jul 2008] |
| Clonality | Monoclonal |
|---|---|
| Isotype | IgG2a |
| Clone Number | 2G5.1 |
| Host Species | Mouse |
| Tested Applications | FACSIHC-FIP |
| Flow Cytometry: 1/50 - 1/100: |
|
| Species Reactivity | HumanRhesus MonkeyCynomolgus Monkey |
| Concentration | 1mg/ml |
| Purification | Affinity purified |
| Gene Synonyms | HUMINAE CD103 integrin alpha E (antigen CD103 human mucosal lymphocyte antigen 1 alpha polypeptide) ITGAE |
|---|---|
| Target | Integrin alpha E |
| Tissue Specificity | This antibody recognizes less than 0.1% bone marrow cells and less than 0.7% PBL. |
| Application Notes | Flow Cytometry: 1/50 - 1/100: |
|---|
| Form | Liquid |
|---|---|
| Storage Instructions | Store at +4°C or at -20°C if preferred. This product should be stored undiluted. Avoid repeated freezing and thawing as this may denature the antibody. Should this product contain a precipitate we recommend microcentrifugation before use. |
| Storage Buffer | Phosphate buffered saline containing 0.09% Sodium Azide 0.5% Bovine Serum Albumin |
