| Product Name | Integrin alpha V antibody |
|---|---|
| Antibody Type | Primary Antibodies |
| Product description | Mouse monoclonal [272-17E6] to Integrin alpha VIntegrin alpha V chain interacts with the integrin beta 3 subunit/CD61 to form the alpha-V-beta-3 heterodimer/vitronectin receptor. It is expressed on endothelial cells, some activated leukocytes, NK cells, macrophages, neutrophils, and platelets. Integrin alpha V also forms heterodimers with the integrin beta 1, beta 5, beta 6, and beta 8 subunits. Alpha-V-beta-3 is an activation dependent receptor for platelet attachment and spreading on vitronectin and other matrix components. |
| Immunogen | Full length native protein (purified) (Human). |
| Clonality | Monoclonal |
|---|---|
| Isotype | IgG1 |
| Clone Number | 272-17E6 |
| Host Species | Mouse |
| Tested Applications | ELISAFACSIHCIP |
| For ELISA: Use at an assay dependent dilution. For FACS, IHC-P and IP: Use at a concentration of 2 - 3μg/ml. Optimal dilutions/concentrations should be determined by the researcher.: |
|
| Species Reactivity | Human |
| Concentration | 0.5mg/ml |
| Gene Synonyms | Integrin alpha V Vitronectin receptor alpha polypeptide antigen CD51 CD51 Msk8 Msk 8 ITGAV VNRA DKFZp686A08142 |
|---|---|
| Target | Integrin alpha V |
| Tissue Specificity | Cross reacts with all alpha V integrins. |
| Cellular Localization | Cell Membrane |
| Application Notes | For ELISA: Use at an assay dependent dilution. For FACS, IHC-P and IP: Use at a concentration of 2 - 3μg/ml. Optimal dilutions/concentrations should be determined by the researcher.: |
|---|
| Form | Liquid |
|---|---|
| Storage Instructions | Upon Receipt - Keep as concentrated solution. Aliquot and store at -20ºC or below. Avoid freeze-thaw cycles. |
| Storage Buffer | PBS, pH 7.6, no preservatives added |
