| Product Name | Integrin beta 3 antibody |
|---|---|
| Antibody Type | Primary Antibodies |
| Product description | Mouse monoclonal [MHF4] to Integrin beta 3Human Integrin beta 3 (CD61) antigen is expressed on platelets, megakaryocytes, macrophages, osteoclasts and synovial lining cells. The integrin beta 3 chain of the vitronectin receptor and GPIIb/IIIa complex. The beta 3 integrin chain is a 90-110 kD glycoprotein polypeptide which is expressed on platelets, megakaryocytes, macrophages, osteoclasts and synovial lining cells. |
| Immunogen | Cell preparation: A bone cell suspension containing osteoclasts, osteoblasts and bone marrow cells obtained from the long bones of newborn Sprague Dawley rats. |
| Clonality | Monoclonal |
|---|---|
| Isotype | IgG1 |
| Clone Number | MHF4 |
| Host Species | Mouse |
| Tested Applications | FACSIHC-FIHC-PIP |
| FACS: Use at an assay dependent dilution. IHC-Fr: Use at an assay dependent dilution. Note: samples should be acetone fixed. IP: Use at an assay dependent dilution. Optimal dilutions/concentrations should be determined by the end user.: |
|
| Species Reactivity | HumanMouseRat |
| Concentration | 1mg/ml |
| Gene Synonyms | CD61 GP3A PLATELET SPECIFIC ANTIGEN YUK NAIT Integrin beta 3 HPA1 Integrin beta3 platelet glycoprotein IIIa precursor PTP ITGB3 HPA 4 HPA 1 Platelet fibrinogen receptor beta subunit HPA4 |
|---|---|
| Target | Integrin beta 3 |
| Tissue Specificity | MHF4 may be used to identify osteoclasts in tissue sections and bone cell suspensions. |
| Cellular Localization | Cell Membrane |
| Application Notes | FACS: Use at an assay dependent dilution. IHC-Fr: Use at an assay dependent dilution. Note: samples should be acetone fixed. IP: Use at an assay dependent dilution. Optimal dilutions/concentrations should be determined by the end user.: |
|---|
| Form | Liquid |
|---|---|
| Storage Instructions | Keep as concentrated solution. Store at 4°C short term. For extended storage aliquot and store at -20°C or below. Avoid freeze-thaw cycles. |
| Storage Buffer | Preservative: None. Constituents: PBS |
