Rabbit Polyclonal antibody to INTS3INTS3 is a subunit of the Integrator complex, which associates with the C-terminal domain of RNA polymerase II large subunit (POLR2A; MIM 180660) and mediates 3-prime end processing of small nuclear RNAs U1 (RNU1; MIM 180680) and U2 (RNU2; MIM 180690) (Baillat et al., 2005 [PubMed 16239144]). INTS3 is also a subunit of single-stranded DNA (ssDNA)-binding complexes involved in the maintenance of genome stability (Huang et al., 2009) [PubMed 19683501].[supplied by OMIM, Feb 2010]
Immunogen
KLH conjugated synthetic peptide derived from human INTS3
Key Feature
Clonality
Polyclonal
Isotype
IgG
Host Species
Rabbit
Tested Applications
IHC-P
IHC-P(1:100-500):
Species Reactivity
Mouse
Predicted Reactivity
Bovine, Rabbit, Horse, Pig, Dog
Concentration
1mg/ml (Please refer to the vial label for the specific concentration)