Application
Western blot analysis of IQSEC2 in SK-N-SH cell lysate with IQSEC2 antibody at 1 ug/ml.Application
Immunohistochemistry of IQSEC2 in mouse brain tissue with IQSEC2 antibody at 5 ug/ml.| Product Name | IQSEC2 antibody |
|---|---|
| Antibody Type | Primary Antibodies |
| Product description | Rabbit Polyclonal antibody to IQSEC2This gene encodes a guanine nucleotide exchange factor for the ARF family of small GTP-binding proteins. The encoded protein is a component of the postsynaptic density at excitatory synapses, and may play a critical role in cytoskeletal and synaptic organization through the activation of selected ARF substrates including ARF1 and ARF6. Mutations in this gene have been implicated in nonsyndromic X-linked mental retardation. Alternatively spliced transcript variants encoding multiple isoforms have been observed for this gene. [provided by RefSeq, Aug 2011] |
| Immunogen | IQSEC2 antibody was raised against an 18 amino acid peptide near the carboxy terminus of human IQSEC2. |
| Clonality | Polyclonal |
|---|---|
| Isotype | IgG |
| Host Species | Rabbit |
| Tested Applications | ELISAIHC-PWB |
| WB: 1 - 2 ug/ml. IHC-P: 5 ug/ml: |
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| Species Reactivity | HumanMouse |
| Concentration | 1mg/ml (Please refer to the vial label for the specific concentration) |
| Purification | Affinity purified |
| Gene Synonyms | BRAG1 IQ motif and Sec7 domain 2 MRX1 |
|---|---|
| Target | IQSEC2 |
| Tissue Specificity | IQSEC2 antibody is human, mouse and rat reactive. At least two isoforms of IQSEC2 are known to exist; this antibody will only detect the larger isoform. IQSEC2 antibody is predicted to not cross-react with IQSEC1. |
Application
Western blot analysis of IQSEC2 in SK-N-SH cell lysate with IQSEC2 antibody at 1 ug/ml.
Application
Immunohistochemistry of IQSEC2 in mouse brain tissue with IQSEC2 antibody at 5 ug/ml.| Application Notes | WB: 1 - 2 ug/ml. IHC-P: 5 ug/ml: |
|---|
| Form | Liquid |
|---|---|
| Storage Instructions | IQSEC2 antibody can be stored at 4°C for three months and -20°C, stable for up to one year. |
| Storage Buffer | IQSEC2 antibody is supplied in PBS containing 0.02% sodium azide. |
