Application
Immunohistochemical analysis of paraffin-embedded mouse muscle, using IVNS1ABP antibody at 1:500 dilution.Application
Sample (30 ug of whole cell lysate) A: U87-MG 7.5% SDS PAGE diluted at 1:1000Application
IVNS1ABP antibody detects IVNS1ABP protein at cytoplasm in mouse kidney by immunohistochemical analysis. Sample: Paraffin-embedded mouse kidney. IVNS1ABP antibody diluted at 1:500.| Product Name | IVNS1ABP antibody |
|---|---|
| Antibody Type | Primary Antibodies |
| Product description | Rabbit Polyclonal antibody to IVNS1ABP (influenza virus NS1A binding protein)Plays a role in cell division and in the dynamic organization of the actin skeleton as a stabilizer of actin filaments by association with F-actin through Kelch repeats. Protects cells from cell death induced by actin destabilization; Protects neurons from dendritic spines and actin filaments damage induced by the actin-destabilizing cytochalasin B when overexpressed. Activates Erk signaling pathway when overexpressed in cultured cell lines (By similarity). May be a component of the cellular splicing machinery with a role in pre-mRNA splicing; may mediate the inhibition of splicing by NS/influenza virus NS1A protein. Functions as modifier of the AHR/Aryl hydrocarbon receptor pathway increasing the concentration of AHR available to activate transcription. |
| Immunogen | Recombinant protein encompassing a sequence within the C-terminus region of human IVNS1ABP. The exact sequence is proprietary. |
| Clonality | Polyclonal |
|---|---|
| Isotype | IgG |
| Host Species | Rabbit |
| Tested Applications | IHC-PWB |
| *Optimal dilutions/concentrations should be determined by the researcher.
: |
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| Species Reactivity | HumanMouse |
| Predicted Reactivity | Rat, Pig, Rhesus Monkey, BovineRat (97%), Pig (95%), Rhesus Monkey (100%), Bovine (95%) |
| Concentration | 0.5mg/ml |
| Purification | Affinity purified |
| Gene Synonyms | DKFZp686K06216 antibody FLARA3 antibody FLJ10069 antibody FLJ10411 antibody FLJ10962 antibody FLJ35593 antibody FLJ36593 antibody HSPC068 antibody KIAA0850 antibody KLHL39 antibody ND1 antibody NS-1 antibody NS1-BP antibody NS1BP antibody IVN |
|---|---|
| Molecular Weight(MW) | 72 kDa (note) (2) |
| Cellular Localization | Cytoplasm , cytoskeleton , Nucleus , nucleoplasm |
Application
Immunohistochemical analysis of paraffin-embedded mouse muscle, using IVNS1ABP antibody at 1:500 dilution.
Application
Sample (30 ug of whole cell lysate) A: U87-MG 7.5% SDS PAGE diluted at 1:1000
Application
IVNS1ABP antibody detects IVNS1ABP protein at cytoplasm in mouse kidney by immunohistochemical analysis. Sample: Paraffin-embedded mouse kidney. IVNS1ABP antibody diluted at 1:500.| Positive Control | NT2D1 , IMR32 , U87-MG , MCF-7 |
|---|---|
| Application Notes | *Optimal dilutions/concentrations should be determined by the researcher.
: |
| Form | Liquid |
|---|---|
| Storage Instructions | Keep as concentrated solution. Aliquot and store at -20ºC or below. Avoid multiple freeze-thaw cycles. |
| Storage Buffer | 0.1M Tris, 0.1M Glycine, 20% Glycerol (pH7). 0.01% Thimerosal was added as a preservative. |
