Rabbit Polyclonal antibody to Jagged 2 (jagged 2)The Notch signaling pathway is an intercellular signaling mechanism that is essential for proper embryonic development. Members of the Notch gene family encode transmembrane receptors that are critical for various cell fate decisions. The protein encoded by this gene is one of several ligands that activate Notch and related receptors. Two transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq]
Immunogen
Recombinant protein encompassing a sequence within the N-terminus region of human Jagged 2. The exact sequence is proprietary.
Key Feature
Clonality
Polyclonal
Isotype
IgG
Host Species
Rabbit
Tested Applications
WB
*Optimal dilutions/concentrations should be determined by the researcher.
:
Species Reactivity
Human
Predicted Reactivity
MouseMouse (98%)
Concentration
1mg/ml
Purification
Affinity purified
Target Information
Gene Synonyms
SER2 jagged 2 JAG2 HJ2
Target
Jagged 2
Molecular Weight(MW)
133 kDa (note) (2)
Cellular Localization
Membrane; Single-pass type I membrane protein
Application
Application
Whole cell extract (30 μg) was separated by 5% SDS-PAGE, and the membrane was blotted with Jagged 2 antibody diluted at 1:1000.
Positive Control
293T
Application Notes
*Optimal dilutions/concentrations should be determined by the researcher.
:
Additional Information
Form
Liquid
Storage Instructions
Keep as concentrated solution. Aliquot and store at -20ºC or below. Avoid multiple freeze-thaw cycles.
Storage Buffer
1XPBS, 20% Glycerol (pH7). 0.025% ProClin 300 was added as a preservative.