Application
Untreated (–) and treated (+) K562 whole cell extracts (60 µg) were separated by 7.5% SDS-PAGE, and the membrane was blotted with JAK2 (phospho Tyr1007/1008) antibody diluted at 1:1000.| Product Name | JAK2 (phospho Tyr1007/1008) antibody |
|---|---|
| Antibody Type | Primary Antibodies |
| Product description | Rabbit Polyclonal antibody to JAK2 (phospho Tyr1007/1008) (Janus kinase 2)This gene product is a protein tyrosine kinase involved in a specific subset of cytokine receptor signaling pathways. It has been found to be constituitively associated with the prolactin receptor and is required for responses to gamma interferon. Mice that do not express an active protein for this gene exhibit embryonic lethality associated with the absence of definitive erythropoiesis. [provided by RefSeq] |
| Immunogen | Carrier-protein conjugated synthetic peptide encompassing a sequence within the C-terminus region of human JAK2 (phospho Tyr1007/1008). The exact sequence is proprietary. |
| Modification | p-Tyr1007/1008 |
| Clonality | Polyclonal |
|---|---|
| Isotype | IgG |
| Host Species | Rabbit |
| Tested Applications | WB |
| *Optimal dilutions/concentrations should be determined by the researcher.
: |
|
| Species Reactivity | Human |
| Predicted Reactivity | Mouse, Rat, Xenopus laevis, Pig, Chicken, Rhesus MonkeyMouse (100%), Rat (100%), Xenopus laevis (100%), Pig (100%), Chicken (100%), Rhesus Monkey (100%) |
| Concentration | 1mg/ml |
| Purification | Affinity purified |
| Target | JAK2 |
|---|---|
| Molecular Weight(MW) | 131 kDa (note) (7) |
| Cellular Localization | Endomembrane system; Peripheral membrane protein (By similarity) |
Application
Untreated (–) and treated (+) K562 whole cell extracts (60 µg) were separated by 7.5% SDS-PAGE, and the membrane was blotted with JAK2 (phospho Tyr1007/1008) antibody diluted at 1:1000.| Positive Control | K562 |
|---|---|
| Application Notes | *Optimal dilutions/concentrations should be determined by the researcher.
: |
| Form | Liquid |
|---|---|
| Storage Instructions | Keep as concentrated solution. Aliquot and store at -20ºC or below. Avoid multiple freeze-thaw cycles. |
| Storage Buffer | 1XPBS, 1% BSA, 20% Glycerol (pH7). 0.025% ProClin 300 was added as a preservative. |
