Application
Immunohistochemistry analysis of paraffin-embedded human brain, using JHD3B Antibody. The picture on the right is treated with the synthesized peptide.| Product Name | JHD3B antibody |
|---|---|
| Antibody Type | Primary Antibodies |
| Product description | Rabbit polyclonal antibody to JHD3BHistone demethylase that specifically demethylates 'Lys-9' of histone H3, thereby playing a role in histone code. Does not demethylate histone H3 'Lys-4', H3 'Lys-27', H3 'Lys-36' nor H4 'Lys-20'. Only able to demethylate trimethylated H3 'Lys-9', with a weaker activity than KDM4A, KDM4C and KDM4D. Demethylation of Lys residue generates formaldehyde and succinate. |
| Immunogen | The antiserum was produced against synthesized peptide derived from human KDM4B. |
| Clonality | Polyclonal |
|---|---|
| Host Species | Rabbit |
| Tested Applications | ELISAIHCIHC-P |
| ELISA: 1:1000Optimal dilutions should be determined experimentally by the end user.: |
|
| Species Reactivity | Human |
| Concentration | 1mg/ml |
| Purification | Affinity purified |
| Gene Synonyms | EC1.14.11. JHD3B Jumonji domain containing protein 2B Jumonji domain containing protein2B JMJ2B EC 1.14.11. EC 1.14.11.- |
|---|---|
| Target | JHD3B |
| Molecular Weight(MW) | 121 kDa (note) |
| Tissue Specificity | JHD3B Antibody detects endogenous levels of total JHD3B protein. |
Application
Immunohistochemistry analysis of paraffin-embedded human brain, using JHD3B Antibody. The picture on the right is treated with the synthesized peptide.| Application Notes | ELISA: 1:1000Optimal dilutions should be determined experimentally by the end user.: |
|---|
| Form | Liquid |
|---|---|
| Storage Instructions | Store at -20 degrees Celcius. Product is stable for at least 1 year. |
| Storage Buffer | Phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150mM NaCl, 0.02% sodium azide and 106% glycerol. |
