Application
Western blot analysis of extracts from Jurkat cells, treated with etoposide 25uM 24h, using Neuropsin (Cleaved-Val33) Antibody. The lane on the right is treated with the synthesized peptide.| Product Name | Kallikrein 8 (cleaved Val33) antibody |
|---|---|
| Antibody Type | Primary Antibodies |
| Product description | Rabbit polyclonal antibody to Kallikrein 8 (cleaved Val33)Serine protease which is capable of degrading a number of proteins such as casein, fibrinogen, kininogen, fibronectin and collagen type IV. Also cleaves L1CAM in response to increased neural activity. Induces neurite outgrowth and fasciculation of cultured hippocampal neurons. Plays a role in the formation and maturation of orphan and small synaptic boutons in the Schaffer-collateral pathway, regulates Schaffer-collateral long-term potentiation in the hippocampus and is required for memory acquisition and synaptic plasticity. Involved in skin desquamation and keratinocyte proliferation. Plays a role in the secondary phase of pathogenesis following spinal cord injury. |
| Clonality | Polyclonal |
|---|---|
| Host Species | Rabbit |
| Tested Applications | ELISAWB |
| ELISA: 1:10000Optimal dilutions should be determined experimentally by the end user.: |
|
| Species Reactivity | Human |
| Concentration | 1mg/ml |
| Purification | Affinity purified |
| Gene Synonyms | HNP TADG14 NRPN Neuropsin NP PRSS19 Neuropsin (cleaved V33) Neuropsin (cleaved Val33) Neuropsin cleaved V33 Neuropsin cleaved Val33 Cleaved Neuropsin (V33) Cleaved Neuropsin (Val33) |
|---|---|
| Target | Kallikrein 8 |
| Molecular Weight(MW) | 24 kDa (note) |
| Tissue Specificity | Kallikrein 8 (Cleaved-Val33) Antibody detects endogenous levels of fragment of activated Neuropsin resulting from cleavage adjacent to Val33. |
| Cellular Localization | Shows a cytoplasmic distribution in the keratinocytes. |
Application
Western blot analysis of extracts from Jurkat cells, treated with etoposide 25uM 24h, using Neuropsin (Cleaved-Val33) Antibody. The lane on the right is treated with the synthesized peptide.| Application Notes | ELISA: 1:10000Optimal dilutions should be determined experimentally by the end user.: |
|---|
| Form | Liquid |
|---|---|
| Storage Instructions | Store at -20 degrees Celcius. Product is stable for at least 1 year. |
| Storage Buffer | Phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol. |
