Rabbit Polyclonal antibody to KCC2 (solute carrier family 12, member 5)Mediates electroneutral potassium-chloride cotransport in mature neurons. Transport occurs under isotonic conditions, but is activated 20-fold by cell swelling. Important for Cl(-) homeostasis in neurons.
Immunogen
Carrier-protein conjugated synthetic peptide encompassing a sequence within the C-terminus region of human KCC2. The exact sequence is proprietary.
Key Feature
Clonality
Polyclonal
Isotype
IgG
Host Species
Rabbit
Tested Applications
WB
*Optimal dilutions/concentrations should be determined by the researcher.
:
Species Reactivity
Human
Predicted Reactivity
MouseMouse (100%)
Concentration
1mg/ml
Purification
Affinity purified
Target Information
Gene Synonyms
KCC2 antibody KCC2 antibody Slc12a5 antibody mKIAA1176 antibody solute carrier family 12 member 5 antibody
Target
KCC2
Molecular Weight(MW)
126 kDa (note)
Cellular Localization
Cell projection , dendrite , Cell membrane; Multi-pass membrane protein
Application
Application
Whole cell extract (30 µg) was separated by 5% SDS-PAGE, and the membrane was blotted with KCC2 antibody diluted at 1:500.
Positive Control
SK-N-SH
Application Notes
*Optimal dilutions/concentrations should be determined by the researcher.
:
Additional Information
Form
Liquid
Storage Instructions
Keep as concentrated solution. Aliquot and store at -20ºC or below. Avoid multiple freeze-thaw cycles.
Storage Buffer
1XPBS, 20% Glycerol (pH7). 0.025% ProClin 300 was added as a preservative.