Rabbit Polyclonal antibody to KCNN4 (potassium intermediate/small conductance calcium-activated channel, subfamily N, member 4)The protein encoded by this gene is part of a potentially heterotetrameric voltage-independent potassium channel that is activated by intracellular calcium. Activation is followed by membrane hyperpolarization, which promotes calcium influx. The encoded protein may be part of the predominant calcium-activated potassium channel in T-lymphocytes. This gene is similar to other KCNN family potassium channel genes, but it differs enough to possibly be considered as part of a new subfamily. [provided by RefSeq]
Immunogen
Carrier-protein conjugated synthetic peptide encompassing a sequence within the C-terminus region of human KCNN4. The exact sequence is proprietary.
Key Feature
Clonality
Polyclonal
Isotype
IgG
Host Species
Rabbit
Tested Applications
WB
*Optimal dilutions/concentrations should be determined by the researcher.
:
Species Reactivity
Human
Predicted Reactivity
Mouse, RatMouse (100%), Rat (100%)
Concentration
1mg/ml
Purification
Affinity purified
Target Information
Gene Synonyms
KCA4 IK1 KCa3.1 IKCA1 hIKCa1 SK4 hKCa4 hSK4 potassium calcium-activated channel subfamily N member 4
Target
KCNN4
Molecular Weight(MW)
48 kDa (note)
Cellular Localization
Membrane; Multi-pass membrane protein
Application
Application
Jurkat whole cell and membrane extracts (30 μg) were separated by 10% SDS-PAGE, and the membrane was blotted with KCNN4 antibody diluted at 1:1000.
Positive Control
Jurkat , Jurkat membrane extract
Application Notes
*Optimal dilutions/concentrations should be determined by the researcher.
:
Additional Information
Form
Liquid
Storage Instructions
Keep as concentrated solution. Aliquot and store at -20ºC or below. Avoid multiple freeze-thaw cycles.
Storage Buffer
1XPBS, 20% Glycerol (pH7). 0.025% ProClin 300 was added as a preservative.