Rabbit Polyclonal antibody to KDM4D (lysine-specific demethylase 4D)Histone demethylase that specifically demethylates 'Lys-9' of histone H3, thereby playing a central role in histone code. Does not demethylate histone H3 'Lys-4', H3 'Lys-27', H3 'Lys-36' nor H4 'Lys-20'. Demethylates both di- and trimethylated H3 'Lys-9' residue, while it has no activity on monomethylated residues. Demethylation of Lys residue generates formaldehyde and succinate.
Immunogen
Recombinant protein encompassing a sequence within the center region of human KDM4D. The exact sequence is proprietary.
Key Feature
Clonality
Polyclonal
Isotype
IgG
Host Species
Rabbit
Tested Applications
WB
*Optimal dilutions/concentrations should be determined by the researcher.
:
Species Reactivity
Human
Predicted Reactivity
Mouse, RatMouse (88%), Rat (86%)
Concentration
1mg/ml (Please refer to the vial label for the specific concentration)
Purification
Affinity purified
Target Information
Gene Synonyms
FLJ10251 antibody JMJD2D antibody MGC141909 antibody KDM4D antibody jumonji domain containing 2D antibody jmjC domain-containing histone demethylation protein 3D antibody jumonji domain-containing protein 2D antibody lysine-specific demethylase 4D a
Molecular Weight(MW)
59 kDa (note) (2)
Cellular Localization
Nucleus
Application
Application
Sample (30 ug of whole cell lysate) A: U87-MG 7.5% SDS PAGE diluted at 1:1000
Positive Control
U87-MG
Application Notes
*Optimal dilutions/concentrations should be determined by the researcher.
:
Additional Information
Form
Liquid
Storage Instructions
Keep as concentrated solution. Aliquot and store at -20ºC or below. Avoid multiple freeze-thaw cycles.
Storage Buffer
1XPBS, 20% Glycerol (pH7). 0.01% Thimerosal was added as a preservative.