Application
Anti-KIF3A Antibody: Immunoperoxidase staining of KIF3A in formalin fixed, paraffin-embedded rat brain at 0.1 μg/mL.Application
Anti-KIF3A Antibody: Immunoperoxidase staining of KIF3A in formalin fixed, paraffin-embedded mouse brain at 0.4 μg/mL.| Product Name | KIF3A antibody |
|---|---|
| Antibody Type | Primary Antibodies |
| Product description | Rabbit polyclonal to KIF3AThe kinesin superfamily (KIFs) of proteins consists of a class of microtubule-dependent motors that plays a major role in many cellular and developmental functions, including organelle transport, mitosis, meiosis, and possibly long-range signaling in neurons. The KIF proteins are primarily associated with anterograde transport of vesicles and organelles in neurons, epithelial cells, and melanosomes with bidirectional transport of mitochondria and mediating transport between the endoplasmic reticulum (ER) and the Golgi complex. KIF3 motor complex is composed of the KIF3A, KIF3B, and KIF3C motor subunits, that associate as heterodimers, in which KIF3B and KIF3C are alternative partners of KIF3A. KIF3A/B has been shown to function in vivo as a motor for the anterograde fast axonal transport of membranebound organelles in neurons. KIF3 plays a crucial role during development. KIF3A-/- and KIF3B-/- mice do not survive beyond midgestation. |
| Immunogen | Synthetic peptide conjugated to KLH, corresponding to amino acids 682-701 of Mouse KIF3A. This sequence is identical in human. |
| Clonality | Polyclonal |
|---|---|
| Isotype | IgG |
| Host Species | Rabbit |
| Tested Applications | ICC/IFIHC-PWB |
| For IF: Use at a dilution of 1:100. For WB: Use at a dilution of 1:2,000. Optimal dilutions/concentrations should be determined by the researcher. | |
| Species Reactivity | HumanMouseRat |
| Concentration | 1mg/ml |
| Purification | Unpurified |
| Gene Synonyms | kinesin family member 3A |
|---|---|
| Target | KIF3A |
Application
Anti-KIF3A Antibody: Immunoperoxidase staining of KIF3A in formalin fixed, paraffin-embedded rat brain at 0.1 μg/mL.
Application
Anti-KIF3A Antibody: Immunoperoxidase staining of KIF3A in formalin fixed, paraffin-embedded mouse brain at 0.4 μg/mL.| Application Notes | For IF: Use at a dilution of 1:100. For WB: Use at a dilution of 1:2,000. Optimal dilutions/concentrations should be determined by the researcher. |
|---|
| Form | Liquid |
|---|---|
| Storage Instructions | Keep as concentrated solution. Store at 4ºC short term. For extended storage aliquot and store at -20ºC or below. Avoid freeze-thaw cycles. |
| Storage Buffer | Phosphate-buffered saline, pH 7.4, containing 15 mM sodium azide |
