WB analysis of rat heart (1 and 3) and rat brain (2 and 4) membranes using Kir2.1 antibody at a dilution of 1:200 in the absence (lens 1 and 2) or presence (lens 3 and 4) of blocking peptide.
Rabbit Polyclonal antibody to Kir2.1Potassium channels are present in most mammalian cells, where they participate in a wide range of physiologic responses. The protein encoded by this gene is an integral membrane protein and inward-rectifier type potassium channel. The encoded protein, which has a greater tendency to allow potassium to flow into a cell rather than out of a cell, probably participates in establishing action potential waveform and excitability of neuronal and muscle tissues. Mutations in this gene have been associated with Andersen syndrome, which is characterized by periodic paralysis, cardiac arrhythmias, and dysmorphic features. [provided by RefSeq, Jul 2008]
Immunogen
Peptide (C)NGVPESTSTDTPPDIDLHN, corresponding to amino acid residues 392-410 of human Kir2.1 (Accession P48049). Intracellular, C-terminal part.
WB analysis of rat heart (1 and 3) and rat brain (2 and 4) membranes using Kir2.1 antibody at a dilution of 1:200 in the absence (lens 1 and 2) or presence (lens 3 and 4) of blocking peptide.
Additional Information
Form
Liquid
Storage Instructions
Keep as concentrated solution. Aliquot and store at -20ºC or below. Avoid multiple freeze-thaw cycles.