Application
Western blot analysis of KIR2DS2 in 293 cell lysate with KIR2DS2 antibody at (A) 1 and (B) 2 ug/ml.| Product Name | KIR2DS2 antibody |
|---|---|
| Antibody Type | Primary Antibodies |
| Product description | Rabbit Polyclonal antibody to KIR2DS2Killer cell immunoglobulin-like receptors (KIRs) are transmembrane glycoproteins expressed by natural killer cells and subsets of T cells. The KIR genes are polymorphic and highly homologous and they are found in a cluster on chromosome 19q13.4 within the 1 Mb leukocyte receptor complex (LRC). The gene content of the KIR gene cluster varies among haplotypes, although several "framework" genes are found in all haplotypes (KIR3DL3, KIR3DP1, KIR3DL4, KIR3DL2). The KIR proteins are classified by the number of extracellular immunoglobulin domains (2D or 3D) and by whether they have a long (L) or short (S) cytoplasmic domain. KIR proteins with the long cytoplasmic domain transduce inhibitory signals upon ligand binding via an immune tyrosine-based inhibitory motif (ITIM), while KIR proteins with the short cytoplasmic domain lack the ITIM motif and instead associate with the TYRO protein tyrosine kinase binding protein to transduce activating signals. The ligands for several KIR proteins are |
| Immunogen | KIR2DS2 antibody was raised against an 18 amino acid peptide near the carboxy terminus of human KIR2DS2. |
| Clonality | Polyclonal |
|---|---|
| Isotype | IgG |
| Host Species | Rabbit |
| Tested Applications | ELISAWB |
| WB: 1 - 2 ug/ml | |
| Species Reactivity | Human |
| Concentration | 1mg/ml (Please refer to the vial label for the specific concentration) |
| Purification | Affinity purified |
| Gene Synonyms | CD158J , CD158b , 183ActI , killer cell immunoglobulin-like receptor, two domains, short cytoplasmic tail, 2 , cl-49 , NKAT5 |
|---|---|
| Target | KIR2DS2 |
| Tissue Specificity | KIR2DS2 antibody is human specific. Multiple isoforms are known to exist. |
Application
Western blot analysis of KIR2DS2 in 293 cell lysate with KIR2DS2 antibody at (A) 1 and (B) 2 ug/ml.| Application Notes | WB: 1 - 2 ug/ml |
|---|
| Form | Liquid |
|---|---|
| Storage Instructions | Be stored at 4oC for three months and -20oC, stable for up to one year. |
| Storage Buffer | PBS containing 0.02% sodium azide. |
