Application
WB analysis of extracts from various cells using KLC1 antibody.Application
IHC-P analysis of human lung cancer using KLC1 antibody at a dilution of 1:200.Application
IHC-P analysis of human liver cancer using KLC1 antibody at a dilution of 1:200.Application
ICC/IF analysis of U20S cells using KLC1 antibody (red) and DAPI (blue).| Product Name | KLC1 antibody |
|---|---|
| Antibody Type | Primary Antibodies |
| Product description | Rabbit Polyclonal antibody to KLC1Conventional kinesin is a tetrameric molecule composed of two heavy chains and two light chains, and transports various cargos along microtubules toward their plus ends. The heavy chains provide the motor activity, while the light chains bind to various cargos. This gene encodes a member of the kinesin light chain family. It associates with kinesin heavy chain through an N-terminal domain, and six tetratricopeptide repeat (TPR) motifs are thought to be involved in binding of cargos such as vesicles, mitochondria, and the Golgi complex. Thus, kinesin light chains function as adapter molecules and not motors per se. Although previously named "kinesin 2", this gene is not a member of the kinesin-2 / kinesin heavy chain subfamily of kinesin motor proteins. Extensive alternative splicing produces isoforms with different C-termini that are proposed to bind to different cargos; however, the full-length nature and/or biological validity of most of these variants have not been determined. [prov |
| Immunogen | Recombinant protein of human KLC1 |
| Clonality | Polyclonal |
|---|---|
| Isotype | IgG |
| Host Species | Rabbit |
| Tested Applications | ICC/IFIHC-PWB |
| WB: 1:500 - 1:2000. IHC: 1:50 - 1:200. IF: 1:50 - 1:200 | |
| Species Reactivity | HumanMouseRat |
| Concentration | 1mg/ml |
| Purification | Affinity purified |
| Gene Synonyms | KNS2 , kinesin light chain 1 , KNS2A , KLC |
|---|---|
| Target | KLC1 |
| Molecular Weight(MW) | 65 kDa (note) |
Application
WB analysis of extracts from various cells using KLC1 antibody.
Application
IHC-P analysis of human lung cancer using KLC1 antibody at a dilution of 1:200.
Application
IHC-P analysis of human liver cancer using KLC1 antibody at a dilution of 1:200.
Application
ICC/IF analysis of U20S cells using KLC1 antibody (red) and DAPI (blue).| Application Notes | WB: 1:500 - 1:2000. IHC: 1:50 - 1:200. IF: 1:50 - 1:200 |
|---|
| Form | Liquid |
|---|---|
| Storage Instructions | Store at -20°C (regular) or -80°C (long term). Avoid freeze / thaw cycles. |
| Storage Buffer | PBS with 0.02% sodium azide, 50% glycerol, pH7.3. |
