Application
Western blot analysis of KPNA2 in rat heart tissue lysate with KPNA2 antibody at (A) 1 and (B) 2 ug/mL.Application
Immunohistochemistry of KPNA2 in human heart tissue with KPNA2 antibody at 5 ug/mL.Application
Immunofluorescence of KPNA2 in human heart tissue with KPNA2 antibody at 20 ug/mL.| Product Name | KPNA2 antibody |
|---|---|
| Antibody Type | Primary Antibodies |
| Product description | Rabbit Polyclonal antibody to KPNA2The import of proteins into the nucleus is a process that involves at least 2 steps. The first is an energy-independent docking of the protein to the nuclear envelope and the second is an energy-dependent translocation through the nuclear pore complex. Imported proteins require a nuclear localization sequence (NLS) which generally consists of a short region of basic amino acids or 2 such regions spaced about 10 amino acids apart. Proteins involved in the first step of nuclear import have been identified in different systems. These include the Xenopus protein importin and its yeast homolog, SRP1 (a suppressor of certain temperature-sensitive mutations of RNA polymerase I in Saccharomyces cerevisiae), which bind to the NLS. KPNA2 protein interacts with the NLSs of DNA helicase Q1 and SV40 T antigen and may be involved in the nuclear transport of proteins. KPNA2 also may play a role in V(D)J recombination [provided by RefSeq, Jul 2008] |
| Immunogen | KPNA2 antibody was raised against a 15 amino acid synthetic peptide near the amino terminus of human KPNA2. |
| Clonality | Polyclonal |
|---|---|
| Isotype | IgG |
| Host Species | Rabbit |
| Tested Applications | ELISAICC/IFIHC-PWB |
| WB: 1 - 2 ug/ml. IHC-P: 5 ug/ml. IF: 20 ug/ml | |
| Species Reactivity | HumanRat |
| Concentration | 1mg/ml (Please refer to the vial label for the specific concentration) |
| Purification | Affinity purified |
| Gene Synonyms | SRP1alpha , karyopherin alpha 2 (RAG cohort 1, importin alpha 1) , QIP2 , RCH1 , IPOA1 |
|---|---|
| Target | KPNA2 |
Application
Western blot analysis of KPNA2 in rat heart tissue lysate with KPNA2 antibody at (A) 1 and (B) 2 ug/mL.
Application
Immunohistochemistry of KPNA2 in human heart tissue with KPNA2 antibody at 5 ug/mL.
Application
Immunofluorescence of KPNA2 in human heart tissue with KPNA2 antibody at 20 ug/mL.| Application Notes | WB: 1 - 2 ug/ml. IHC-P: 5 ug/ml. IF: 20 ug/ml |
|---|
| Form | Liquid |
|---|---|
| Storage Instructions | Be stored at 4oC for three months and -20oC, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures. |
| Storage Buffer | PBS containing 0.02% sodium azide. |
