Application
WB analysis of ZR-75-1, K562 and NCI-H460 cell lysates (35ug/lane) using Kremen-2 antibody.| Product Name | Kremen-2 antibody |
|---|---|
| Antibody Type | Primary Antibodies |
| Product description | Rabbit polyclonal antibody to Kremen-2This gene encodes a high-affinity dickkopf homolog 1 (DKK1) transmembrane receptor. A similar protein in mouse functions interacts with with DKK1 to block wingless (WNT)/beta-catenin signaling. The encoded protein forms a ternary membrane complex with DKK1 and the WNT receptor lipoprotein receptor-related protein 6 (LRP6), and induces rapid endocytosis and removal of LRP6 from the plasma membrane. It contains extracellular kringle, WSC, and CUB domains. Alternatively spliced transcript variants encoding distinct isoforms have been observed for this gene. [provided by RefSeq, Dec 2011] |
| Immunogen | This antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 248-276 amino acids from the central region of human Kremen-2. |
| Clonality | Polyclonal |
|---|---|
| Isotype | IgG |
| Host Species | Rabbit |
| Tested Applications | WB |
| WB : 1:1000 |
|
| Species Reactivity | Human |
| Concentration | 0.5mg/ml |
| Purification | Protein A |
| Gene Synonyms | kringle containing transmembrane protein 2 , KRM2 |
|---|---|
| Target | KREMEN2 |
Application
WB analysis of ZR-75-1, K562 and NCI-H460 cell lysates (35ug/lane) using Kremen-2 antibody.| Application Notes | WB : 1:1000 |
|---|
| Form | Liquid |
|---|---|
| Storage Instructions | Maintain refrigerated at 2-8°C for up to 6 months. For long term storage store at -20°C in small aliquots to prevent freeze-thaw cycles. |
| Storage Buffer | Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide |
