Rabbit Polyclonal antibody to KRT75This gene is a member of the type II keratin family clustered on the long arm of chromosome 12. Type I and type II keratins heteropolymerize to form intermediate-sized filaments in the cytoplasm of epithelial cells. This gene is expressed in the companion layer, upper germinative matrix region of the hair follicle, and medulla of the hair shaft. The encoded protein plays an essential role in hair and nail formation. Variations in this gene have been associated with the hair disorders pseudofolliculitis barbae (PFB) and loose anagen hair syndrome (LAHS). [provided by RefSeq, Oct 2008]
Immunogen
A synthetic peptide corresponding to an Internal region of Human KRT75
Key Feature
Clonality
Polyclonal
Isotype
IgG
Host Species
Rabbit
Tested Applications
WB
*Optimal dilutions/concentrations should be determined by the researcher.
Species Reactivity
Human
Predicted Reactivity
Dog: 79%; Human: 100%; Rabbit: 86%
Concentration
1mg/ml
Purification
Affinity purified
Target Information
Gene Synonyms
PFB , K6HF , KB18 , KRT75
Target
KRT75
Molecular Weight(MW)
60 KDa (note)
Application
Application
WB analysis of human small intestine tissue using KRT75 antibody at 0.2-1μg/ml.
Positive Control
human small intestine
Application Notes
*Optimal dilutions/concentrations should be determined by the researcher.
Additional Information
Form
Liquid
Storage Instructions
Keep as concentrated solution. For short-term storage, store at 4ºC. For long-term storage, aliquot and store at -20ºC or below. Avoid multiple freeze-thaw cycles.
Storage Buffer
1x PBS buffer with 0.09% (w/v) sodium azide and 2% sucrose.