Application
Western blot analysis of Ku70 (AcK542) expression in A549 (A); HeLa (B) whole cell lysates.| Product Name | Ku70 (Acetyl Lys542) antibody |
|---|---|
| Antibody Type | Primary Antibodies |
| Product description | Rabbit Polyclonal antibody to Ku70 (Acetyl Lys542)The p70/p80 autoantigen is a nuclear complex consisting of two subunits with molecular masses of approximately 70 and 80 kDa. The complex functions as a single-stranded DNA-dependent ATP-dependent helicase. The complex may be involved in the repair of nonhomologous DNA ends such as that required for double-strand break repair, transposition, and V(D)J recombination. High levels of autoantibodies to p70 and p80 have been found in some patients with systemic lupus erythematosus. [provided by RefSeq, Jul 2008] |
| Immunogen | KLH-conjugated synthetic peptide encompassing a sequence within the C-term region of human Ku70. The exact sequence is proprietary. |
| Modification | Acetyl Lys542 |
| Clonality | Polyclonal |
|---|---|
| Isotype | IgG |
| Host Species | Rabbit |
| Tested Applications | WB |
| WB: 1:500 - 1:1000: |
|
| Species Reactivity | Human |
| Concentration | 1mg/ml |
| Purification | Affinity purified |
| Gene Synonyms | X-ray repair complementing defective repair in Chinese hamster cells 6 G22P1 TLAA CTCBF ML8 KU70 XRCC6 CTC75 |
|---|---|
| Target | Ku70 (Acetyl Lys542) |
| Tissue Specificity | Recognizes endogenous levels of Ku70 (AcK542) protein. |
Application
Western blot analysis of Ku70 (AcK542) expression in A549 (A); HeLa (B) whole cell lysates.| Application Notes | WB: 1:500 - 1:1000: |
|---|
| Form | Liquid |
|---|---|
| Storage Instructions | Shipped at 4 °C. Upon delivery aliquot and store at -20 °C for one year. Avoid freeze/thaw cycles. |
| Storage Buffer | Liquid in 0.42% Potassium phosphate; 0.87% Sodium chloride; pH 7.3; 30% glycerol; and 0.01% sodium azide. |
