| Product Name | Kv1.1 antibody |
|---|---|
| Antibody Type | Primary Antibodies |
| Product description | Rabbit polyclonal antibody to Kv1.1This gene encodes a voltage-gated delayed potassium channel that is phylogenetically related to the Drosophila Shaker channel. The encoded protein has six putative transmembrane segments (S1-S6), and the loop between S5 and S6 forms the pore and contains the conserved selectivity filter motif (GYGD). The functional channel is a homotetramer. The N-terminus of the channel is associated with beta subunits that can modify the inactivation properties of the channel as well as affect expression levels. The C-terminus of the channel is complexed to a PDZ domain protein that is responsible for channel targeting. Mutations in this gene have been associated with myokymia with periodic ataxia (AEMK). [provided by RefSeq, Jul 2008] |
| Clonality | Polyclonal |
|---|---|
| Isotype | IgG |
| Host Species | Rabbit |
| Tested Applications | ELISAIHC-PWB |
| P-ELISA:1:500-1000, WB:1:100-500, IHC-P:1:100-500 (based on 0.5 mg/ml) | |
| Species Reactivity | HumanMouseDogPigRatHorseSheepBovine |
| Concentration | 0.5mg/ml |
| Purification | Affinity purified |
| Gene Synonyms | HUK1 , RBK1 , HBK1 , AEMK , EA1 , MBK1 , KCNA1 , KV1.1 , potassium voltage-gated channel, shaker-related subfamily, member 1 (episodic ataxia with myokymia) , MK1 |
|---|---|
| Target | BKCa channel |
| Application Notes | P-ELISA:1:500-1000, WB:1:100-500, IHC-P:1:100-500 (based on 0.5 mg/ml) |
|---|
| Form | Liquid |
|---|---|
| Storage Instructions | Store at 4°C for up to two weeks. For long term storage, aliquot and store at -20°C, avoid freeze/thaw cycles. |
| Storage Buffer | 10 mM PBS, pH 7.4 with 10 mg/ml BSA and 0.1% sodium azide. |
