Application
Sample (30 ug of whole cell lysate) A: IMR32 7.5% SDS PAGE diluted at 1:1000IF
Colocalization with the ER marker calnexin (in green) revealed that mutant Kv4.3 proteins (in red) were retained in the ER, as was shown by the merged picture (in yellow).| Product Name | Kv4.3 antibody , C-term |
|---|---|
| Antibody Type | Primary Antibodies |
| Product description | Rabbit Polyclonal antibody to Kv4.3 (potassium voltage-gated channel, Shal-related subfamily, member 3)Voltage-gated potassium (Kv) channels represent the most complex class of voltage-gated ion channels from both functional and structural standpoints. Their diverse functions include regulating neurotransmitter release, heart rate, insulin secretion, neuronal excitability, epithelial electrolyte transport, smooth muscle contraction, and cell volume. Four sequence-related potassium channel genes - shaker, shaw, shab, and shal - have been identified in Drosophila, and each has been shown to have human homolog(s). This gene encodes a member of the potassium channel, voltage-gated, shal-related subfamily, members of which form voltage-activated A-type potassium ion channels and are prominent in the repolarization phase of the action potential. This member includes two isoforms with different sizes, which are encoded by alternatively spliced transcript variants of this gene. [provided by RefSeq] |
| Immunogen | Recombinant protein encompassing a sequence within the C-terminus region of human Kv4.3. The exact sequence is proprietary. |
| Clonality | Polyclonal |
|---|---|
| Isotype | IgG |
| Host Species | Rabbit |
| Tested Applications | ICC/IFIFWB |
| *Optimal dilutions/concentrations should be determined by the researcher.
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| Species Reactivity | Human |
| Predicted Reactivity | Mouse, Rat, Rabbit, Chicken, Rhesus Monkey, BovineMouse (98%), Rat (99%), Rabbit (97%), Chicken (84%), Rhesus Monkey (100%), Bovine (100%) |
| Concentration | 1mg/ml |
| Purification | Affinity purified |
| Gene Synonyms | KCND3L antibody KCND3S antibody KSHIVB antibody KV4.3 antibody MGC142035 antibody MGC142037 antibody KCND3 antibody potassium ionic channel Kv4.3 antibody potassium voltage-gated channel subfamily D member 3 antibody voltage-gated potassium channe |
|---|---|
| Molecular Weight(MW) | 73 kDa (note) (3) |
| Cellular Localization | Membrane; Multi-pass membrane protein , Cell membrane , sarcolemma |
Application
Sample (30 ug of whole cell lysate) A: IMR32 7.5% SDS PAGE diluted at 1:1000
IF
Colocalization with the ER marker calnexin (in green) revealed that mutant Kv4.3 proteins (in red) were retained in the ER, as was shown by the merged picture (in yellow).| Positive Control | IMR32 , U87-MG |
|---|---|
| Application Notes | *Optimal dilutions/concentrations should be determined by the researcher.
: |
| Form | Liquid |
|---|---|
| Storage Instructions | Keep as concentrated solution. Aliquot and store at -20ºC or below. Avoid multiple freeze-thaw cycles. |
| Storage Buffer | 1XPBS, 1% BSA, 20% Glycerol (pH7). 0.01% Thimerosal was added as a preservative. |
