Rabbit Polyclonal antibody to Lamin B ReceptorThe protein encoded by this gene belongs to the ERG4/ERG24 family. It localized in the nuclear envelope inner membrane and anchors the lamina and the heterochromatin to the membrane. It may mediate interaction between chromatin and lamin B. Mutations of this gene has been associated with autosomal recessive HEM/Greenberg skeletal dysplasia. Alternative splicing occurs at this locus and two transcript variants encoding the same protein have been identified. [provided by RefSeq, Jul 2008]
Immunogen
Recombinant protein of human LBR
Key Feature
Clonality
Polyclonal
Isotype
IgG
Host Species
Rabbit
Tested Applications
IHCIHC-PWB
WB 1:500 - 1:2000, IHC 1:50 - 1:200, IF 1:50 - 1:200, IP 1:20 - 1:50:
Species Reactivity
HumanMouse
Concentration
1mg/ml
Purification
Affinity purified
Target Information
Gene Synonyms
DHCR14B TDRD18 PHA lamin B receptor LBR LMN2R
Target
Lamin B Receptor
Molecular Weight(MW)
71 kDa (note)
Application
Application
Western blot analysis of extracts of various cell lines, using LBR antibody.
Application
Immunohistochemistry of paraffin-embedded rat brain using LBR antibody at dilution of 1:200 (400x lens).
Application Notes
WB 1:500 - 1:2000, IHC 1:50 - 1:200, IF 1:50 - 1:200, IP 1:20 - 1:50: