Mouse monoclonal antibody [2D9G5] to Laminin beta 1Laminins, a family of extracellular matrix glycoproteins, are the major noncollagenous constituent of basement membranes. They have been implicated in a wide variety of biological processes including cell adhesion, differentiation, migration, signaling, neurite outgrowth and metastasis. Laminins are composed of 3 non identical chains: laminin alpha, beta and gamma (formerly A, B1, and B2, respectively) and they form a cruciform structure consisting of 3 short arms, each formed by a different chain, and a long arm composed of all 3 chains. Each laminin chain is a multidomain protein encoded by a distinct gene. Several isoforms of each chain have been described. Different alpha, beta and gamma chain isomers combine to give rise to different heterotrimeric laminin isoforms which are designated by Arabic numerals in the order of their discovery, i.e. alpha1beta1gamma1 heterotrimer is laminin 1. The biological functions of the different chains and trimer molecules are largely unknown, but s
Immunogen
The immunogen corresponding to a region within amino acids 31 and 270 of LAMB1 expressed in E. Coli.
Key Feature
Clonality
Monoclonal
Isotype
IgG2a
Clone Number
2D9G5
Host Species
Mouse
Tested Applications
ELISAIHC-PWB
ELISA: 1/10000.:
Species Reactivity
Human
Concentration
1mg/ml
Target Information
Gene Synonyms
CLM LIS5
Target
LAMB1
Cellular Localization
Major component.
Application
Application
Immunohistochemical analysis of paraffin-embedded human thyroid tissues using LAMB1 mouse mAb
Application
Western blot analysis using anti-LAMB1 monoclonal antibody against truncated LAMB1-His recombinant protein(1).
Application Notes
ELISA: 1/10000.:
Additional Information
Form
Liquid
Storage Instructions
Store at 4℃, for long term storage, store at -20℃.