Rabbit Polyclonal antibody to LEFTY2 (left-right determination factor 2)This gene encodes a member of the TGF-beta family of proteins. The encoded protein is secreted and plays a role in left-right asymmetry determination of organ systems during development. The protein may also play a role in endometrial bleeding. Mutations in this gene have been associated with left-right axis malformations, particularly in the heart and lungs. Some types of infertility have been associated with dysregulated expression of this gene in the endometrium. Alternative processing of this protein can yield three different products. This gene is closely linked to both a related family member and a related pseudogene. [provided by RefSeq]
Immunogen
Recombinant protein encompassing a sequence within the center region of human LEFTY2. The exact sequence is proprietary.
Key Feature
Clonality
Polyclonal
Isotype
IgG
Host Species
Rabbit
Tested Applications
IHC-PWB
*Optimal dilutions/concentrations should be determined by the researcher.
:
Species Reactivity
Human
Predicted Reactivity
Mouse, Rat, Pig, BovineMouse (84%), Rat (83%), Pig (83%), Bovine (84%)
Concentration
1mg/ml
Purification
Affinity purified
Target Information
Gene Synonyms
EBAF antibody LEFTA antibody LEFTYA antibody MGC46222 antibody TGFB4 antibody LEFTY2 antibody left-right determination factor A antibody protein lefty-2 antibody endometrial bleeding-associated factor antibody left-right determination factor 2 ant
Molecular Weight(MW)
41 kDa (note) (2)
Cellular Localization
Secreted
Application
Application
Immunohistochemical analysis of paraffin-embedded human colon carcinoma, using LEFTY2 antibody at 1:500 dilution.
Application
Sample (30 ug of whole cell lysate) A: A431 10% SDS PAGE diluted at 1:1000
Positive Control
A431
Application Notes
*Optimal dilutions/concentrations should be determined by the researcher.
:
Additional Information
Form
Liquid
Storage Instructions
Keep as concentrated solution. Aliquot and store at -20ºC or below. Avoid multiple freeze-thaw cycles.
Storage Buffer
0.1M Tris, 0.1M Glycine, 10% Glycerol (pH7). 0.01% Thimerosal was added as a preservative.