| Product Name | Leptin antibody |
|---|---|
| Antibody Type | Primary Antibodies |
| Product description | Mouse monoclonal antibody [9L19] to LeptinThis gene encodes a protein that is secreted by white adipocytes, and which plays a major role in the regulation of body weight. This protein, which acts through the leptin receptor, functions as part of a signaling pathway that can inhibit food intake and/or regulate energy expenditure to maintain constancy of the adipose mass. This protein also has several endocrine functions, and is involved in the regulation of immune and inflammatory responses, hematopoiesis, angiogenesis and wound healing. Mutations in this gene and/or its regulatory regions cause severe obesity, and morbid obesity with hypogonadism. This gene has also been linked to type 2 diabetes mellitus development. [provided by RefSeq, Jul 2008] |
| Immunogen | Human recombinant Leptin |
| Clonality | Monoclonal |
|---|---|
| Isotype | IgG1 |
| Clone Number | 9L19 |
| Host Species | Mouse |
| Tested Applications | NeutWB |
| WB(1:500-1000)|Neutralization of Leptin bioactivity: |
|
| Species Reactivity | Human |
| Concentration | 1mg/ml |
| Purification | Affinity purified |
| Gene Synonyms | leptin LEPD LEP OB OBS |
|---|---|
| Target | Leptin |
| Tissue Specificity | This antibody was selected for its ability to specifically detect human Leptin. |
| Application Notes | WB(1:500-1000)|Neutralization of Leptin bioactivity: |
|---|
| Form | Liquid |
|---|---|
| Storage Instructions | Keep as concentrated solution. Aliquot and store at -20ºC or below. Avoid multiple freeze-thaw cycles. |
| Storage Buffer | PBS |
