Rabbit polyclonal antibody to Lipin 2Lipin 2 is a nuclear protein that belongs to the evolutionarily conserved Lipin family. Studies show that a mutation to human Lipin 2 is linked to autosomal dominant high grade myopia and Majeed syndrome.
Key Feature
Clonality
Polyclonal
Isotype
IgG
Host Species
Rabbit
Tested Applications
WB
Western blotting (0.5-4 µg/ml). It detects a band between 70-100 kDa, corresponding to the molecular mass of Lipin-2. A lower band ~55 kDa can also be detected, presumably to be the cleavage fragment of Lipin-2.
Species Reactivity
HumanMouseRat
Concentration
0.5mg/ml
Purification
Affinity purified
Target Information
Gene Synonyms
LPIN2, KIAA0249
Target
Lipin 2
Tissue Specificity
This antibody is specific for Lipin 2.
Cellular Localization
Translocates from cytosol to endoplasmic reticulum membrane with increasing levels of oleate.
Application
Application
Western blot analysis of Lipin 2 expression in Jurkat (Lane 1) and 3T3 (Lane 2) cell lysates.
Application Notes
Western blotting (0.5-4 µg/ml). It detects a band between 70-100 kDa, corresponding to the molecular mass of Lipin-2. A lower band ~55 kDa can also be detected, presumably to be the cleavage fragment of Lipin-2.
Additional Information
Form
Liquid
Storage Instructions
The antibody solution should be gently mixed before use. Stored at -20 °C for future use.