Application
LITAF antibody [N1C3] detects LITAF protein at cytoplasm on human placenta by immunohistochemical analysis. Sample: Paraffin-embedded placenta. LITAF antibody [N1C3] dilution: 1:100.Application
Sample (30 ug of whole cell lysate) A: Hep G2 12% SDS PAGE diluted at 1:1000| Product Name | LITAF antibody |
|---|---|
| Antibody Type | Primary Antibodies |
| Product description | Rabbit polyclonal antibody to LITAF (lipopolysaccharide-induced TNF factor)Lipopolysaccharide is a potent stimulator of monocytes and macrophages, causing secretion of tumor necrosis factor-alpha (TNF-alpha) and other inflammatory mediators. This gene encodes lipopolysaccharide-induced TNF-alpha factor, which is a DNA-binding protein and can mediate the TNF-alpha expression by direct binding to the promoter region of the TNF-alpha gene. The transcription of this gene is induced by tumor suppresor p53 and has been implicated in the p53-induced apoptotic pathway. Mutations in this gene cause Charcot-Marie-Tooth disease type 1C (CMT1C) and may be involved in the carcinogenesis of extramammary Paget's disease (EMPD). Multiple alternatively spliced transcript variants have been found for this gene. [provided by RefSeq] |
| Immunogen | Recombinant protein encompassing a sequence within the center region of human LITAF. The exact sequence is proprietary. |
| Clonality | Polyclonal |
|---|---|
| Isotype | IgG |
| Host Species | Rabbit |
| Tested Applications | IHC-PIPWBChIP |
| Not tested in other applications. | |
| Species Reactivity | Human |
| Predicted Reactivity | Mouse, Rat, Rhesus Monkey, BovineMouse (85%), Rat (86%), Rhesus Monkey (96%), Bovine (86%) |
| Concentration | 1mg/ml (Please refer to the vial label for the specific concentration) |
| Purification | Affinity purified |
| Gene Synonyms | FLJ38636 antibody, MGC116698 antibody, MGC116700 antibody, MGC116701 antibody, MGC125274 antibody, MGC125275 antibody, MGC125276 antibody, PIG7 antibody, SIMPLE antibody, TP53I7 antibody, LITAF antibody, LPS-induced TNF-alpha factor antibody, p53-induced g |
|---|---|
| Target | LITAF |
| Molecular Weight(MW) | 17 kDa (note) (2) |
| Cellular Localization | Lysosome membrane; Peripheral membrane protein; Cytoplasmic side |
Application
LITAF antibody [N1C3] detects LITAF protein at cytoplasm on human placenta by immunohistochemical analysis. Sample: Paraffin-embedded placenta. LITAF antibody [N1C3] dilution: 1:100.
Application
Sample (30 ug of whole cell lysate) A: Hep G2 12% SDS PAGE diluted at 1:1000| Positive Control | HeLa , HepG2 |
|---|---|
| Application Notes | Not tested in other applications. |
| Form | Liquid |
|---|---|
| Storage Instructions | Keep as concentrated solution. Aliquot and store at -20ºC or below. Avoid multiple freeze-thaw cycles. |
| Storage Buffer | 0.1M Tris, 0.1M Glycine, 10% Glycerol (pH7). 0.01% Thimerosal was added as a preservative. |
