Application
Western blot analysis of LKB1 (pS428) expression in HeLa UV-treated (A); NIH3T3 UV-treated (B); mouse brain (C); PC12 UV-treated (D) whole cell lysates.| Product Name | LKB1 (phospho Ser428) antibody |
|---|---|
| Antibody Type | Primary Antibodies |
| Product description | Rabbit Polyclonal antibody to LKB1 (phospho Ser428)This gene, which encodes a member of the serine/threonine kinase family, regulates cell polarity and functions as a tumor suppressor. Mutations in this gene have been associated with Peutz-Jeghers syndrome, an autosomal dominant disorder characterized by the growth of polyps in the gastrointestinal tract, pigmented macules on the skin and mouth, and other neoplasms. Alternate transcriptional splice variants of this gene have been observed but have not been thoroughly characterized. [provided by RefSeq, Jul 2008] |
| Immunogen | KLH-conjugated synthetic peptide encompassing a sequence within the C-term region of human LKB1. The exact sequence is proprietary. |
| Modification | p-Ser428 |
| Clonality | Polyclonal |
|---|---|
| Isotype | IgG |
| Host Species | Rabbit |
| Tested Applications | WB |
| WB: 1:500 - 1:1000 | |
| Species Reactivity | HumanMouseRat |
| Concentration | 1mg/ml |
| Purification | Affinity purified |
| Gene Synonyms | STK11 , PJS , hLKB1 , LKB1 , serine/threonine kinase 11 |
|---|---|
| Target | LKB1 (phospho Ser428) |
| Tissue Specificity | Recognizes endogenous levels of LKB1 (pS428) protein. |
Application
Western blot analysis of LKB1 (pS428) expression in HeLa UV-treated (A); NIH3T3 UV-treated (B); mouse brain (C); PC12 UV-treated (D) whole cell lysates.| Application Notes | WB: 1:500 - 1:1000 |
|---|
| Form | Liquid |
|---|---|
| Storage Instructions | Shipped at 4 °C. Upon delivery aliquot and store at -20 °C for one year. Avoid freeze/thaw cycles. |
| Storage Buffer | Liquid in 0.42% Potassium phosphate; 0.87% Sodium chloride; pH 7.3; 30% glycerol; and 0.01% sodium azide. |
