Rabbit Polyclonal antibody to LKB1This gene, which encodes a member of the serine/threonine kinase family, regulates cell polarity and functions as a tumor suppressor. Mutations in this gene have been associated with Peutz-Jeghers syndrome, an autosomal dominant disorder characterized by the growth of polyps in the gastrointestinal tract, pigmented macules on the skin and mouth, and other neoplasms. Alternate transcriptional splice variants of this gene have been observed but have not been thoroughly characterized. [provided by RefSeq, Jul 2008]
Immunogen
LKB1 antibody was raised against a 15 amino acid synthetic peptide from near the carboxy terminus of human LKB1.
Key Feature
Clonality
Polyclonal
Isotype
IgG
Host Species
Rabbit
Tested Applications
ELISAWB
WB: 1 ug/ml
Species Reactivity
Human
Concentration
1mg/ml (Please refer to the vial label for the specific concentration)
Purification
Affinity purified
Target Information
Gene Synonyms
serine/threonine kinase 11 , STK11 , hLKB1 , PJS
Target
LKB1
Application
Application
Western blot analysis of LKB1 in PC-3 cell lysate with LKB1 antibody at 1 ug/mL in the (A) absence or (B) presence of blocking peptide.
Application Notes
WB: 1 ug/ml
Additional Information
Form
Liquid
Storage Instructions
Be stored at 4oC for three months and -20oC, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.