Rabbit Polyclonal antibody to LOXL1 (lysyl oxidase-like 1)This gene encodes a member of the lysyl oxidase gene family. The prototypic member of the family is essential to the biogenesis of connective tissue, encoding an extracellular copper-dependent amine oxidase that catalyses the first step in the formation of crosslinks in collagens and elastin. A highly conserved amino acid sequence at the C-terminus end appears to be sufficient for amine oxidase activity, suggesting that each family member may retain this function. The N-terminus is poorly conserved and may impart additional roles in developmental regulation, senescence, tumor suppression, cell growth control, and chemotaxis to each member of the family. [provided by RefSeq]
Immunogen
Recombinant protein encompassing a sequence within the center region of human LOXL1. The exact sequence is proprietary.
Key Feature
Clonality
Polyclonal
Isotype
IgG
Host Species
Rabbit
Tested Applications
WB
*Optimal dilutions/concentrations should be determined by the researcher.
Species Reactivity
Human
Predicted Reactivity
Mouse, Rat, Zebrafish, Xenopus laevis, BovineMouse (98%), Rat (97%), Zebrafish (87%), Xenopus laevis (91%), Bovine (99%)
Concentration
1mg/ml (Please refer to the vial label for the specific concentration)