Rabbit Polyclonal antibody to LOXL4 (lysyl oxidase-like 4)This gene encodes a member of the lysyl oxidase gene family. The prototypic member of the family is essential to the biogenesis of connective tissue, encoding an extracellular copper-dependent amine oxidase that catalyses the first step in the formation of crosslinks in collagens and elastin. A highly conserved amino acid sequence at the C-terminus end appears to be sufficient for amine oxidase activity, suggesting that each family member may retain this function. The N-terminus is poorly conserved and may impart additional roles in developmental regulation, senescence, tumor suppression, cell growth control, and chemotaxis to each member of the family. [provided by RefSeq]
Immunogen
Recombinant protein encompassing a sequence within the center region of human LOXL4. The exact sequence is proprietary.
Key Feature
Clonality
Polyclonal
Isotype
IgG
Host Species
Rabbit
Tested Applications
WB
*Optimal dilutions/concentrations should be determined by the researcher.
Predicted Reactivity
Human, Mouse, Rat, BovineHuman (100%), Mouse (92%), Rat (91%), Bovine (90%)
Concentration
1mg/ml (Please refer to the vial label for the specific concentration)
Purification
Affinity purified
Target Information
Gene Synonyms
FLJ21889 antibody, LOXC antibody, LOXL4 antibody, lysyl oxidase related C antibody, lysyl oxidase homolog 4 antibody, lysyl oxidase-like protein 4 antibody, lysyl oxidase-related protein C antibody, lysyl oxidase-like 4 antibody
Molecular Weight(MW)
84 kDa (note)
Cellular Localization
Secreted , extracellular space
Application Notes
*Optimal dilutions/concentrations should be determined by the researcher.
Additional Information
Form
Liquid
Storage Instructions
Keep as concentrated solution. Aliquot and store at -20ºC or below. Avoid multiple freeze-thaw cycles.
Storage Buffer
1XPBS, 1% BSA, 20% Glycerol (pH7). 0.01% Thimerosal was added as a preservative.