Rabbit polyclonal antibody to LRFN4LRFN4 is one of a family of five transmembrane glycoproteins that are highly expressed in neuronal tissues. LRFN proteins share leucine-rich repeat (LRR)-immunoglobulin-like (Ig)-fibronectin type III (Fn)-transmembrane domain structure with other members of the LRR-Ig-Fn protein superfamily such as the Slitrk family of proteins. Expression of LRFN1, -3, and -4 mRNA was detected in embryonic neuronal cells, while Lrfn2 and Lrfn5 expression was primarily restricted to more mature cells. LRFN1, -2, and -4 bound to PDZ domains of postsynaptic PSD95, re-distributing PSD95 to the cell periphery. It has been suggested that the Lrfn proteins play a role in the developing and/or mature vertebrate nervous system. At least two isoforms of LRFN4 are known to exist. This antibody is predicted to not cross-react with other members of the LRFN family.
Key Feature
Clonality
Polyclonal
Host Species
Rabbit
Tested Applications
ELISAIHC-PWB
Species Reactivity
HumanMouseRat
Concentration
1mg/ml
Purification
Affinity purified
Target Information
Gene Synonyms
LRFN4, SALM3, FIGLER6, synaptic adhesionlike molecule3, Leucinerich repeat and fibronectin typeIII domaincontaining protein 4, synaptic adhesionlike molecule 3, Leucine-rich repeat and fibronectin typeIII domain-containing protein 4, Leucinerich repeat and
Target
LRFN4
Tissue Specificity
This antibody is specific for LRFN4
Application
Application
Immunohistochemistry of LRFN4 in mouse brain tissue with LRFN4 antibody at 2.5 ug/ml.
Application
Western blot analysis of LRFN4 in rat brain lysate with LRFN4 antibody at 1 ug/ml.
Additional Information
Form
Liquid
Storage Instructions
Keep as concentrated solution. Aliquot and store at -20ºC or below. Avoid multiple freeze-thaw cycles.